IS OBESITY ASSOCIATED WITH PROGRESSION OF STEROID-RESISTANT NEPHROTIC SYNDROME IN CHILDREN?
https://doi.org/10.24884/1561-6274-2017-21-2-56-61
Abstract
THE AIM: to study potential associations of obesity with progression of idiopathic steroid-resistant nephrotic syndrome (SRNS) in children. PATIENTS AND METHODS. We performed a retrospective one-center 15-years follow up study of SRNS course in 65 children divided into 2 groups: 1) with obesity (n=48); 2) with normal weight or overweight (n=17). RESULTS. In patients with SRNS and obesity we found no associations with clinical predictors of unfavorable outcome – arterial hypertension and proteinuria and also with glomerular filtration rate at recent hospitalization. Renal survival was comparable between SRNS patients with obesity and normal weight or overweight. CONCLUSION. Obesity does not have any impact on course and prognosis of SRNS in children and can not be considered as risk factor for the disease progression.
About the Authors
L. S. Prikhodina
Pirogov Russian National Research Medical University;
Medical Continuous Postgraduate Education
Russian Federation
Russian Federation
Prof. Larisa S. Prikhodina, MD, PhD.
Division of Inherited and Acquired Kidney Diseases, Research Clinical Institute for Pediatrics n.a. acad. Y.E. Veltishev.
125412 Moscow, Taldomskaya St., 2.
S. V. Papizh
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Svetlana V. Papizh, MD, PhD.
Division of Inherited and Acquired Kidney Diseases, Research Clinical Institute for Pediatrics n.a. acad. Y.E. Veltishev.
125412 Moscow, Taldomskaya St., 2.
M. V. Lebedenkova
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Marina V. Lebedenkova, MD.
Division of Inherited and Acquired Kidney Diseases, Research Clinical Institute for Pediatrics n.a. acad. Y.E. Veltishev.
125412 Moscow, Taldomskaya St., 2.
E. S. Stolyarevich
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs; Moscow University of Medicine and Dentistry; City Clinical Hospital №52 Department of Health in Moscow, Moscow City Nephrology Center
Russian Federation
Russian Federation
Ekaterina S. Stolyarevich, MD, DMedSci.
123182 Moscow, Shchukinskaya Str., d. 1
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Review
For citations:
Prikhodina L.S., Papizh S.V., Lebedenkova M.V., Stolyarevich E.S. IS OBESITY ASSOCIATED WITH PROGRESSION OF STEROID-RESISTANT NEPHROTIC SYNDROME IN CHILDREN? Nephrology (Saint-Petersburg). 2017;21(2):56-61. (In Russ.) https://doi.org/10.24884/1561-6274-2017-21-2-56-61
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