KIDNEY FUNCTION AT PATIENTS BEFORE AND AFTER RADICAL NEPHRECTOMY FOR RENAL CANCER
https://doi.org/10.24884/1561-6274-2013-17-5-83-88
Abstract
Preservation of the renal function is the principal task in treatment of tumors of the kidneys. The studies performed over recent decades show that chronic kidney diseases (CKD) are much more widespread than it was presumed earlier, while the traditional methods used for assessment of the renal function often underrate the occurrence of the CKD, which carries more serious consequences than previously thought. The CKD lead to disorder of the renal functions with subsequent transition to renal insufficiency, which heightens the risk of development and progression of cardiovascular diseases. In patients with renal cell cancer (RCC) the differences between the oncospecific and the overall survival rates become significant as early as three years after the surgical treatment. One of the significant reasons for the absence of positive changes in the overall survival of the RCC patients is deterioration of the renal function after surgical removal of the renal tissue against the background of CKD. Different studies show that the combination of RCC and CKD leading to deterioration of the renal function is found in a substantial number of patients. Thus, the modern therapy for RCC patients must focus on optimization of the renal functions, prevention of CKD, and minimization of the CKD degree, whenever possible. Research aimed at improvement of the renal function in CKD patients after surgery should be one of the priorities of oncourology.
About the Authors
M. I. KoganRussian Federation
A. A. Gusev
Russian Federation
S. V. Yevseev
Russian Federation
References
1. Gupta K, Miller JD, Li JZ, Russell MW, Charbonneau C. Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): a literature review. Cancer Treat Rev 2008; 34:193–205
2. Jemal A, Siegel R, Ward E et al. Cancer statistics, 2009; CA Cancer J Clin 2009; 59:225–249
3. Чиссов ВИ, Старинский ВВ, Петрова ГВ. Злокачественные новообразования в России в 2008 году. М., 2010
4. Гусев АА, Медведев ВЛ, Шангичев АВ и др. Оценка течения инцидентального и симптомного почечно-клеточного рака после радикального лечения. Онкоурология 2006; (4): 18-24
5. Dulabon LM, Lowrance WT, Russo P et al. Trends in renal tumor surgery delivery within the United States. Cancer 2010; 116: 2316
6. Novick AC, Campbell SC, Belldegrun A et al. Guideline for мanagement of the сlinical stage 1 renal mass. J Urol 2009; 182: 1271
7. Kim HL, Shah SK, Tan W, Shikanov SA et al. Estimation and prediction of renal function in patients with renal tumor. J Urol 2009; 181: 2451-2461
8. Lopes NH, Paulitsch FS, Pereira A et al. Mild chronic kidney dysfunction and treatment strategies for stable coronary artery disease. J Thorac Cardiovasc Surg 2009; 137: 1443–1449
9. Jeon HG, Jeong IG, Lee JW et al. Prognostic factors for chronic kidney disease after curative surgery in patients with small renal tumors. Urology 2009; 74: 1064–1069
10. Go AS, Chertow GM, Fan D et al. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351: 1296-1306
11. Levey AS, Coresh J, Balk E, et al. National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann Intern Med. 2003;139:137- 147
12. Панина ИЮ, Румянцев АШ, Меншутина МА и др. Особенности функции эндотелия при хронической болезни почек. Обзор литературы и собственные данные. Нефрология 2007; 11(4):28-46
13. Смирнов АВ, Добронравов ВА, Каюков ИГ и др. Хроническая болезнь почек: основные принципы скрининга, диагностики, профилактики и подходы к лечению. Национальные рекомендации. Нефрология 2012; 16(1): 89-115
14. Есаян АМ, Аль-Шукри СХ, Мосоян МС. Почечноклеточный рак и хроническая болезнь почек: внимание к отдаленным неонкологическим исходам. Нефрология; 16(4): 94-99
15. Lane BR, Poggio ED, Herts BR et al. Renal function assessment in the era of chronic kidney disease: renewed emphasis on renal function centered patient care. J Urol 2009; 182: 435-444
16. Huang WC, Levey AS, Serio AM et al. Chronic kidney disease after nephrectomy in patients with renal cortical tumours: a retrospective cohort study. Lancet Oncol 2006; 7:735-740
17. Clark MA, Shikanov SA, Raman JD et al. Chronic kidney disease before and after partial nephrectomy. J Urol 2011; 185: 43-48
18. Lucas SM, Stern JM, Adibi M et al. Renal function outcomes in patients treated for renal masses smaller than 4 centimetres by ablative and extirpative techniques. J Urol 2008; 179:75-79
19. Funahashi Y, Hattori R, Yamamoto T et al. Relationship between renal parenchymal volume and single kidney glomerular filtration rate before and after unilateral nephrectomy. Urology 2011; 77: 1404–1408
20. Lane BR, Fergany AF, Weight CJ, Campbell SC. Renal functional outcomes after partial nephrectomy with extended ischemic intervals are better than after radical nephrectomy. J Urol 2010; 184: 1286-1290
21. Demirjian S, Weight CJ, Larson BT et al. Performance of the chronic kidney disease-epidemiology study equations for estimating glomerular filtration rate before and after nephrectomy. J Urol 2010; 183: 896-902
Review
For citations:
Kogan M.I., Gusev A.A., Yevseev S.V. KIDNEY FUNCTION AT PATIENTS BEFORE AND AFTER RADICAL NEPHRECTOMY FOR RENAL CANCER. Nephrology (Saint-Petersburg). 2013;17(5):83-88. (In Russ.) https://doi.org/10.24884/1561-6274-2013-17-5-83-88