ИНГИБИЦИЯ РЕНИН-АНГИОТЕНЗИН-АЛЬДОСТЕРОНОВОЙ СИСТЕМЫ И НЕФРОПРОТЕКЦИЯ
https://doi.org/10.24884/1561-6274-2011-15-2-30-42
Аннотация
В обзоре на основании анализа мультицентровых исследований обсуждаются механизмы нефро и кардиопротекции ингибиторами ангиотезин Iпревращающего фермента (ИАПФ) и блокаторами рецепторов ангиотензина (БРА), применение которых для лечения кардиологических больных и пациентов с диабетической и недиабетической нефропатиями постоянно увеличивается. Очерчены ситуации, при которых назначение блокаторов ренинангиотензинальдостероновой
системы (РААС) малоперспективно. У пожилых больных с высоким сердечнососудистым риском применение ИАПФ и БРА, особенно в сочетанном варианте, чревато развитием серьезных осложнений, включая ухудшение функции почек.
системы (РААС) малоперспективно. У пожилых больных с высоким сердечнососудистым риском применение ИАПФ и БРА, особенно в сочетанном варианте, чревато развитием серьезных осложнений, включая ухудшение функции почек.
Об авторах
В. М. ЕРМОЛЕНКО
Российская медицинская академия последипломного образования
Россия
Кафедра нефрологии и гемодиализа
Россия
Кафедра нефрологии и гемодиализа
Н. Н. ФИЛАТОВА
Российская медицинская академия последипломного образования
Россия
Кафедра нефрологии и гемодиализа
Россия
Кафедра нефрологии и гемодиализа
А. Ю. НИКОЛАЕВ
Российская медицинская академия последипломного образования
Россия
Кафедра нефрологии и гемодиализа
Россия
Кафедра нефрологии и гемодиализа
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Рецензия
Для цитирования:
ЕРМОЛЕНКО В.М., ФИЛАТОВА Н.Н., НИКОЛАЕВ А.Ю. ИНГИБИЦИЯ РЕНИН-АНГИОТЕНЗИН-АЛЬДОСТЕРОНОВОЙ СИСТЕМЫ И НЕФРОПРОТЕКЦИЯ. Нефрология. 2011;15(2):30-42. https://doi.org/10.24884/1561-6274-2011-15-2-30-42
For citation:
ERMOLENKO V.M., FILATOVA N.N., NIKOLAEV A.Y. INHIBITION OF RENNIN-ANGIOTENSIN-ALDOSTERONE SYSTEM AND NEPHROPROTECTION. Nephrology (Saint-Petersburg). 2011;15(2):30-42. (In Russ.) https://doi.org/10.24884/1561-6274-2011-15-2-30-42
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