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КАЧЕСТВО ЖИЗНИ И КЛИНИКО-ЛАБОРАТОРНАЯ ХАРАКТЕРИСТИКА РЕЦИПИЕНТОВ ПОЧЕЧНОГО ТРАНСПЛАНТАТА

https://doi.org/10.24884/1561-6274-2013-17-2-66-74

Abstract

THE AIM of the study was to examine the relationship of quality of life (QoL) and clinical and laboratory characteristics of renal transplant recipients (RTR). PATIENTS AND METHODS. The survey of 86 RTR included studying QoL using the general questionnaire SF-36. The nature of the disease, leading to end-stage renal failure, duration of renal replacement therapy before renal transplantation, type of donor, kidney graft function in the early postoperative period, the base immunosuppressive drug, duration of the functioning graft, the presence/absence of chronic graft dysfunction, number of comorbidities, the need for antihypertensive therapy, body mass index, the level of hemoglobin, albumin of the blood were analyzed. RESULTS. The main impact of the majority of clinical and laboratory symptoms traced in patients' satisfaction regarding their physical condition. Greatest importance were pre-transplant diabetes mellitus, delayed graft function and duration of functioning renal transplant, the value of the glomerular filtration rate and albuminemia. Not found to significant effect of the therapy on QoL of RTR. Related kidney recipients were given a higher score of QoL compared to cadaveric transplantation. CONCLUSION. The combination of subjective and objective measures of health forms the most complete picture of condition of patients with transplanted kidney, allows to predict QoL of patient with transplanted kidney, and correction of modifiable clinical and laboratory changes can improve satisfaction of RTR of health-related quality of life.

About the Authors

N. N. Pikalova
Новосибирский государственный медицинский университет
Russian Federation


E. A. Movchan
Новосибирский государственный медицинский университет
Russian Federation


N. L. Tov
Новосибирский государственный медицинский университет
Russian Federation


E. V. Galkina
Новосибирская областная клиническая больница
Russian Federation


N. A. Golovkova
Новосибирская областная клиническая больница
Russian Federation


References

1. Новик АА, Ионова ТИ. Руководство по исследованию качества жизни в медицине. СПб.: ОлмаМедиа Групп; 2007: 17-18

2. Гурылева МЭ, Журавлева МВ, Алеева ГН. Критерии качества жизни в медицине и кардиологии. Русский медицинский журнал 2006; (10): 761-764

3. KDIGO Clinical Practice Guideline for the Care of Kidney Transplant Recipients. Am J Transplant 2009;9 (Suppl 3):S1-155

4. Волынчик ЕП, Каабак ММ, Стенина ИИ и др. Некоторые аспекты изучения качества жизни реципиентов после трансплантации почки. Вестник трансплантологии и искусственных органов 2009; 11(4): 26-29

5. Петрова НН. Концепция качества жизни у больных на заместительной почечной терапии. Нефрология и диализ 2002; (1): 9-14

6. Столяревич ЕС. Хроническая дисфункция трансплантированной почки: морфологическая картина, особенности течения, подходы к профилактике и лечению: Автореф. дис. ... д-ра. мед. наук. М., 2010: 50

7. Charlson ME, Pompei P, Ales KL et al. A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chron Dis 1987; №40 (5): 373-383

8. Ware JE, Kosinski M, Bjorner JB et al. User’s manual for the SF-36v2 TM health survey. 2nd ed. Lincoln: Quality Metric Incorporated 2007

9. Аткинс РК, Циммет П. Диабетическая почка: действуй сейчас или заплатишь потом. Нефрология и диализ 2009; (4): 272-275

10. Gross CR, Limwattananon C, Matthees B. Impact of transplantation on quality of life in patients with diabetes and renal dysfunction. Transplantation 2000; 70(12): 1736-1746

11. Matas AJ, McHugh L, Payne WD et al. Long-term quality of life after kidney and simultaneous pancreas-kidney transplantation. Clin Transplant 1998; 12(3): 233-242

12. Griva K, Ziegelmann JP, Thompson D, Jayasena D et al. Quality of life and emotional responses in cadaver and living related renal transplant recipients. Nephrol Dial Transplant 2002; 17(12): 2204-2211

13. Meier-Kriesche HU, Schold JD. The impact of pretransplant dialysis on outcomes in renal transplantation. Semin Dial 2005; 18(6): 499-504

14. Shield C F, Grath M M, Goss T F. Assessment of health-related quality of life in kidney transplant patients receiving tacrolimus (FK506)-based versus cyclosporine-based immunosuppression. FK506 Kidney Transplant Study Group. Transplantation 1997; 64 (12): 1738-1743

15. Prihodova L, Nagyova I, Rosenberger J. et al. Impact of personality and psychological distress on health-related quality of life in kidney transplant recipients. Transpl Int 2010; 23(5): 484-492

16. Мойсюк ЯГ, Шаршаткин АВ, Арутюнян СМ и др. Трансплантация почки от живого родственного донора. Нефрология и диализ 2001; 3(3): 328-334

17. Halloran PF. Delayed graft function: state of the Art. Am J of Transplant 2001; (1): 115–120

18. Ким ИГ, Столяревич ЕС, Артюхина ЛЮ и др. Влияние режима поддерживающей иммуносупрессивной терапии на отдалённые результаты трансплантации почки. Нефрология и диализ 2012; 14 (1): 41-47

19. Bohlke M, Marini SS, Rocha M et al. Factors associated with health-related quality of life after successful kidney transplantation: a population-based study. Qual Life Res 2009; 18(9):1185-1193

20. Fujisawa M, Ichikawa Y, Yoshiya K. et al. Assessment of health-related quality of life in renal transplant and hemodialysis patients using the SF-36 health survey. Urology 2000; 56(2): 201-206

21. Reimer J, Franke GH, Philipp T, Heemann U. Quality of life in kidney recipients: comparison of tacrolimus and cyclosporinemicroemulsion. Clin Transplant 2002; 16(1): 48-54

22. Choukroun G, Kamar N, Dussol B. Correction of postkidney transplant anemia reduces progression of allograft nephropathy. J Am Soc Nephrol 2012; 23(2): 360-368

23. Rebollo P, Ortega F, Baltar JM et al. Health related quality of life (HRQOL) of kidney transplanted patients: variables that influence it. Clin Transplant 2000; 14(3): 199-207

24. Rebollo P, Baltar JM, Campistol JM et al. Quality of life of patients with chronic renal allograft rejection and anemia. J Nephrol 2004; 17(4): 531-536

25. Pischon T, Sharma A M. Obesity as a risk factor in renal transplant patients. Nephrol Dial Transplant 2001; 16(1): 14-17

26. Schalk BW, Visser M, Bremmer MA et al. Change of Serum Albumin and Risk of Cardiovascular Disease and All-Cause Mortality Longitudinal Aging Study Amsterdam. Am J Epidemiol 2006; 164 (10): 969-977

27. Ujszaszi A, Czira ME, Fornadi K et al. Quality of life and protein-energy wasting in kidney transplant recipients. Int Urol Nephrol 2012; 44 (4): 1257-1268


Review

For citations:


Pikalova N.N., Movchan E.A., Tov N.L., Galkina E.V., Golovkova N.A. КАЧЕСТВО ЖИЗНИ И КЛИНИКО-ЛАБОРАТОРНАЯ ХАРАКТЕРИСТИКА РЕЦИПИЕНТОВ ПОЧЕЧНОГО ТРАНСПЛАНТАТА. Nephrology (Saint-Petersburg). 2013;17(2):66-74. (In Russ.) https://doi.org/10.24884/1561-6274-2013-17-2-66-74

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ISSN 1561-6274 (Print)
ISSN 2541-9439 (Online)