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VASOMOTOR FORM OF ENDOTHELIAL DYSFUNCTION IN CHRONIC KIDNEY DISEASE

https://doi.org/10.24884/1561-6274-2006-10-2-33-37

Abstract

THE AIM of the work was to study the features of the endothelial dysfunction in patients with chronic kidney disease (CKD) at the preclinical stage of atherosclerosis depending on the type of hyperlipoproteidemia. PATIENTS AND METHODS. The investigation included 180 patients with CKD having no clinical signs of atherosclerosis. Parameters of lipidogram, lipid peroxidation, intima-media thickness, reactivity of microvasculature were determined. RESULTS.Lowering glomerular filtration rate was accompanied by disturbances of endothelium-independent and thenendothelium-dependent vasodilatations. CONCLUSION. CKD is an independent factor contributing to impairment of vessel functions.

About the Author

I. Yu. Panina
Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова
Russian Federation


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Review

For citations:


Panina I.Yu. VASOMOTOR FORM OF ENDOTHELIAL DYSFUNCTION IN CHRONIC KIDNEY DISEASE. Nephrology (Saint-Petersburg). 2006;10(2):33-37. (In Russ.) https://doi.org/10.24884/1561-6274-2006-10-2-33-37

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ISSN 1561-6274 (Print)
ISSN 2541-9439 (Online)