ЦИСТАТИН С В СОВРЕМЕННОЙ МЕДИЦИНЕ
https://doi.org/10.24884/1561-6274-2012-16-1-22-39
Аннотация
В обзоре рассмотрены возможности применения эндогенного индикатора функционального состояния почек – цистатина С (Цис С). Дана оценка результатам использования Цис С как маркера скорости клубочковой фильтрации (СКФ) у взрослых и детей. Проанализированы перспективы применения этого параметра в диагностике острого повреждения почек. Оценена также целесообразность его использования в кардиологии и диабетологии. Имеющиеся данные позволяют полагать, что это соединение может давать довольно объективную оценку величины СКФ. При этом, Цис С, по-видимому, несколько превосходит другие рутинные методы определения СКФ в у детей и пациентов с сахарным диабетом. Тем не менее, результаты применения Цис С в клинической практике не однозначны и требуют дальнейших исследований.
Об авторах
И. Г. КаюковРоссия
Научно-исследовательский институт нефрологии
кафедра нефрологии и диализа
197022, Санкт-Петербург, ул. Л. Толстого, д. 17. Тел.: (812)- 346-39-26
А. В. Смирнов
Россия
Научно-исследовательский институт нефрологии
кафедра пропедевтики внутренних болезней
В. Л. Эмануэль
Россия
кафедра клинической лабораторной диагностики
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Рецензия
Для цитирования:
Каюков И.Г., Смирнов А.В., Эмануэль В.Л. ЦИСТАТИН С В СОВРЕМЕННОЙ МЕДИЦИНЕ. Нефрология. 2012;16(1):22-39. https://doi.org/10.24884/1561-6274-2012-16-1-22-39
For citation:
Kayukov I.G., Smirnov A.V., Emanuel V.L. CYSTATIN C IN CURRENT MEDICINE. Nephrology (Saint-Petersburg). 2012;16(1):22-39. (In Russ.) https://doi.org/10.24884/1561-6274-2012-16-1-22-39