COMPARISON OF DIURETIC ACTIVITY OF ARBUTIN AND HYDROQUINONE AT VARIOUS INTRODUCTION WAYS IN EXPERIMENTS ON RATS
https://doi.org/10.24884/1561-6274-2012-16-4-84-87
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Abstract
AIM OF RESEARCH: to compare diuretic activity of arbutin and gidroquinon. MATERIALS AND METHODS: reference material of arbutin and chemically clean gidroquinon was inserted to rats orally and parenterally in doses of 18 mcM/kg and 54 mcM/kg. Diuretic activity of substances was evaluated by urinary volume. In urine fixed sodium and porassium ions. RESULTS: at oral insertion arbutin and gidroquinon have diuretic activity. Most likely that diurectic activity of arbutin and gidroquinon responds to their metabolites.
About the Authors
N. L. Voloboy
ГБОУ ВПО «Алтайский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию»
Russian Federation
Russian Federation
I. V. Smirnov
ГБОУ ВПО «Алтайский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию»
Russian Federation
Russian Federation
A. A. Bondarev
ГБОУ ВПО «Алтайский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию»
Russian Federation
Russian Federation
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Review
For citations:
Voloboy N.L., Smirnov I.V., Bondarev A.A. COMPARISON OF DIURETIC ACTIVITY OF ARBUTIN AND HYDROQUINONE AT VARIOUS INTRODUCTION WAYS IN EXPERIMENTS ON RATS. Nephrology (Saint-Petersburg). 2012;16(4):84-87. (In Russ.) https://doi.org/10.24884/1561-6274-2012-16-4-84-87
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ISSN 1561-6274 (Print)
ISSN 2541-9439 (Online)
ISSN 2541-9439 (Online)
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