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Диабетическая нефропатия - фокус на повреждение подоцитов

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Аннотация

В настоящем обзоре подробно рассмотрены механизмы повреждения подоцитов при сахарном диабете, их взаимосвязь с метаболическими и гемодинамическими нарушениями, представлены результаты последних экспериментальных и клинических исследований по данным вопросам. Авторами освещены биомаркеры, отражающие выраженность подоцитарной дисфункции и структурно-функциональных изменений в нефроне при диабетической нефропатии, обсуждены современные возможности коррекции данных нарушений с целью предупреждения прогрессирования поражения почек.

Об авторах

И. Н. Бобкова
Научно-исследовательский институт профессионального образования; Первый Московский государственный медицинский университет им. И.М. Сеченова
Россия


М. В. Шестакова
Эндокринологический научный центр
Россия


А. А. Щукина
Первый Московский государственный медицинский университет им. И.М. Сеченова
Россия


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Для цитирования:


Бобкова И.Н., Шестакова М.В., Щукина А.А. Диабетическая нефропатия - фокус на повреждение подоцитов. Нефрология. 2015;19(2):33-44.

For citation:


Bobkova I.N., Shestakova M.V., Schukina A.A. Diabetic nephropathy - focus on podocytes damage. Nephrology (Saint-Petersburg). 2015;19(2):33-44. (In Russ.)

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