HISTOPHYSIOLOGY OF THE SUPERFICIAL AND JUXTAMEDULLARY VASCULAR RENAL GLOMERULI AFTER ACUTE MASSIVE BLOOD LOSS
https://doi.org/10.24884/1561-6274-2007-11-2-68-71
Abstract
THE AIM of the investigation was to study the state of juxtaglomerular apparatus (JGA) and capillaries of the superficial and juxtamedullary vascular renal glomeruli after acute massive blood loss. MATERIAL AND METHODS. The degree of opening the capillaries (DOCC) of the superficial and juxtamedullary vascular glomeruli, the ultrastructure of JGA were studied morphologically in experiments in 60 outbred white male rats with body mass 120-140g before and after acute massive blood-etting (on average 3.0 cm³ or 2.5% of the body mass) in 1, 2 and 24 hours. RESULTS. Within 1-2 hours after blood loss the lessening of the circulating blood volume causes a spasm of the afferent and dilatation of the efferent arterioles, the capillaries of the superficial and juxtamedullary vascular glomeruli have mainly I and II DOCC (up to 20%); the average value of DOCC in both cortex zones smoothes down. JGA is in the state of functional stress. Within 24 hours after blood loss DOCC and JGA structure become almost normal. CONCLUSION. The data obtained suggest that activity of the superficial and juxtamedullary vascular glomeruli under physiological conditions and after acute massive blood-letting is regulated by activity of JGA.
About the Authors
A. Yu. Yuldashev
Ташкентская медицинская академия
Uzbekistan
Uzbekistan
R. R. Rakhmanov
Ташкентская медицинская академия
Uzbekistan
Uzbekistan
A. A. Yuldashev
Ташкентская медицинская академия
Uzbekistan
Uzbekistan
M. V. Tarinova
Ташкентская медицинская академия
Uzbekistan
Uzbekistan
References
1. Bosch JP, Saccaggi A, Laner A et al. Renal functional reserve in humans. Am J Med 1983; 75 (4): 943 – 950
2. Волощенко АА, Талалаев СВ. Новый подход к выяснению гистофизиологических процессов в почечных клубочках. Нефрология 1999; 3 (2): 30 – 33
3. Кучер АГ, Есаян АМ, Шишкина ЛИ и др. Влияние нагрузок растительным животным белком на функциональное состояние почек у здоровых людей.Нефрология 1997; 1 (2): 79 – 84
4. De Santo NG, Anastasio P, Cirillo et al. Sequential analysis of variation in glomerular filtration rate to calculate the haemodynamic response to meal meat. Nephrol Dial Transplant 1995; 10 [Suppl 9]: 1629 – 1636
5. Гоженко АИ, Куксань НИ, Гоженко ЕА. Методика определения почечного функционального резерва. Нефрология 2001; 5 (4): 70 – 73
6. Beuknof HR, ter Wee PR, Sluiter WJ, Donker AJM. Renal reserve filtration capacity befor and after kidney donation. Am J Nephrol 1985; 5 (1): 267 – 270
7. Zuccala A, Zucchellii P. Use and misuse of renal functional reserve concept in clinical nephrology. Nephrol Dial Transplant 1990; 5 [Suppl 2]: 410 – 417
8. Рябов СИ, Наточин ЮВ. Функциональная нефрология. Лань, СПб., 1997; 5 – 27
9. Лакин ГФ. Биометрия. Высшая школа, М., 1980; 40 – 66
10. Крыжановский ГН. Некоторые закономерности осуществления биологических процессов и их роль в патологии. Патол физиол эксперим терапия 1974; (6): 3 – 15
11. Куприянов ВВ, Караганов ЯЛ, Козлов ВИ. Микроциркуляторное русло. Медицина, М., 1975; 136 – 155
12. Зуфаров КА, Юлдашев АЮ. Тонкая кишка. В: Руководство по гистологии. СпецЛит, СПб, 2002; 115 – 140
13. Анохин ПК. Очерки по физиологии функциональных систем. Медицина, М., 1975; 275 – 291
14. Юлдашев АЮ, Рахманов РР, Юлдашев МА. Принципы системогенеза и особенности нефрогенеза. Мед журнал Узбекистана 2005; (6): 51 – 56
Review
For citations:
Yuldashev A.Yu., Rakhmanov R.R., Yuldashev A.A., Tarinova M.V. HISTOPHYSIOLOGY OF THE SUPERFICIAL AND JUXTAMEDULLARY VASCULAR RENAL GLOMERULI AFTER ACUTE MASSIVE BLOOD LOSS. Nephrology (Saint-Petersburg). 2007;11(2):68-71. (In Russ.) https://doi.org/10.24884/1561-6274-2007-11-2-68-71
Views:
413
Email this article 