MORPHOLOGICAL ASSESSMENT OF ACUTE POISONINGS WITH PALLID TOADSTOOL

Abstract

THE AIM of the investigation was to detect specific clinicomorphological features appearing in acute poisonings with pallid toadstools. MATERIAL AND METHODS. An analysis was made of 2 case histories of hospital patients and 4 acts (conclusions) of medicolegal experts on examination of corpses of subjects dead from poisonings with toadstools. Under investigation there were 30 micropreparations of kidneys and liver stained with hematoxylin and eosin. RESUILTS. Characteristic clinical symptoms of poisoning were found as well as the following morphological alterations: in the liver widely spread necroses of hepatocytes; in the kidneys steatosis and dysproteinosis with the formation in basal parts of the cells of convoluted tubules of small vacuoles containing lipids with swelling and pronounced granular structure of cytoplasm, in the collecting tubules granular cylinders. CONCLUSION. Specific features found in histological investigation point to the development of severe dystrophic changes.