SECONDARY ANTIPHOSPHOLIPID SYNDROME IN COMBINED LIVER AND KIDNEY LESION IN PATIENTS WITH CHRONIC ALCOHOLISM
https://doi.org/10.24884/1561-6274-2004-8-4-52-56
Abstract
THE AIM of the study was to verify antiphospholipid syndrome in patients with chronic alcoholism accompanied by the liver and kidney lesion, to determine the interrelations between clinical and immunological manifestations of antiphospholipid syndrome and cholesterol metabolism status, lipoproteins. MATERIALS AND METHODS. One hundred and eleven male patients with chronic alcoholism having kidney lesion were examined. Blood serum level of ApoV was determined using the method of hard phasic immunofermental analysis according to L.M.Polyakov. RESULTS. The highest blood serum level of ApoV in combination with marked impairments of the albumin transport function was revealed in patients with chronic alcoholism with kidney lesions. CONCLUSION. Chronic alcoholism patients with kidney lesions in 80,7% of cases develop secondary antiphospholipid syndrome with morphological alterations to kidney tissues by the ischemic and necrotic type.
About the Authors
N. S. Tarasova
Городская больница №2, Комсомольск-на-Амуре,
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
E. I. Beloborodova
Городская больница №2, Комсомольск-на-Амуре,
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
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Review
For citations:
Tarasova N.S., Beloborodova E.I. SECONDARY ANTIPHOSPHOLIPID SYNDROME IN COMBINED LIVER AND KIDNEY LESION IN PATIENTS WITH CHRONIC ALCOHOLISM. Nephrology (Saint-Petersburg). 2004;8(4):52-56. (In Russ.) https://doi.org/10.24884/1561-6274-2004-8-4-52-56
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