MORPHOLOGICAL RISK FACTORS OF LOCAL RECURRENCE AFTER RADICAL PROSTATECTOMY
https://doi.org/10.24884/1561-6274-2004-8-4-89-91
Abstract
THE AIM of the investigation was to find out morphological risk factors and to make a mathematical prognostic model of a local recurrence of tumor in patients with prostate cancer after radical prostatectomy. PATIENTS AND METHODS. An analysis of incidence of local recurrences of tumor in 150 patients with localized forms of prostate cancer after radical retropubic prostatectomy was made with special reference to the results of morphological investigation. RESULTS. A local recurrence of tumor after radical prostatectomy took place in 13 (8.7%) patients. The leading morphological risk factors of its appearance (the greatest coefficient of factor load, F) were: positive surgical edge (F=54,20, growth of tumor into the seminal vesicles (F=31.56%) and metastases in the regional lymph nodes (F=21.14). A mathematical model allowing prognosis of its appearance with 84.6% probability was made on the basis of the analysis of morphological factors of risk of recurrence of prostate cancer. CONCLUSION. The assessment of probability of the appearance of local recurrence of tumor is necessary for planning the treatment of the patients after radical prostatectomy with special reference to morphological risk factors.
About the Authors
S. Yu. Borovets
Санкт-Петербургский государственный медицинский университет им.акад. И.П. Павлова
Russian Federation
Russian Federation
V. V. Kozlov
Санкт-Петербургский государственный медицинский университет им.акад. И.П. Павлова
Russian Federation
Russian Federation
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Review
For citations:
Borovets S.Yu., Kozlov V.V. MORPHOLOGICAL RISK FACTORS OF LOCAL RECURRENCE AFTER RADICAL PROSTATECTOMY. Nephrology (Saint-Petersburg). 2004;8(4):89-91. (In Russ.) https://doi.org/10.24884/1561-6274-2004-8-4-89-91
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