MECHANICAL ACTIVITY, R HYTHMOINOTROPIC RELATIONSHIPS IN MYOCARDIUM OF RATS AND DEFICIENCY OF MINERAL SUBSTANCES IN DRINKING WATER
https://doi.org/10.24884/1561-6274-2003-7-4-71-75
Abstract
THE AIM of the work was to comparatively investigate the mechanical properties of the myocardium of rats receiving difinitive diet. MATERIAL AND METHODS. An analysis of myocardium contractility of rats drinking water with normal low content of Ca ++ and Mg ++ cations was carried out under conditions of isometric and physiological regimens of mechanical loading. RESULTS. Under conditions of normal content of calcium (120 mg/l) and magnesium (45 mg/l) in drinking water the rats showed increased contractility of the myocardium followed by delayed relaxation in all end-systolic lengths as compared to the parameters registered in the animals given water with low concentrations of calcium and magnesium (St. Petersburg pipe water). CONCLUSION. The myocardium of rats drinking water with normal concentration of calcium and magnesium is characterized by well pronounced Bowditch scale and post-stimulation potentiation unlike the animals given water with low concentration of calcium and magnesium.
About the Authors
T. A. Barabanova
Институт физиологии им. акад. И.П. Павлова РАН
Russian Federation
Russian Federation
S. K. Churina
Институт физиологии им. акад. И.П. Павлова РАН
Russian Federation
Russian Federation
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Review
For citations:
Barabanova T.A., Churina S.K. MECHANICAL ACTIVITY, R HYTHMOINOTROPIC RELATIONSHIPS IN MYOCARDIUM OF RATS AND DEFICIENCY OF MINERAL SUBSTANCES IN DRINKING WATER. Nephrology (Saint-Petersburg). 2003;7(4):71-75. (In Russ.) https://doi.org/10.24884/1561-6274-2003-7-4-71-75
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