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ERYTHROCYTE SEDIMENTATION RATE AND ARTERIAL COMPLIANCE IN PRE-DIALYSIS PATIENTS

https://doi.org/10.24884/1561-6274-2003-7-1-62-66

Abstract

Damage of the vessels is associated with inflammation. The erythrocyte sedimentation rate (ESR) is a simple method of assessment of the clinical status. The aim of this study was to estimate the relationship between the ESR and total arterial compliance assessed by stroke volume/pulse pressure ratio (SV/PP ratio) in non-diabetic pre-dialysis patients. Sixty seven non-diabetic pre-dialysis patients (36 males and 31 females, mean age 51 ±11 years) were studied. 51 patients (76.1 %) had arterial hypertension. Serum creatinine was 215.8±139.5 mmol/l, hemoglobin concentration -124.1 ±17.3 (range 75-163) g/l, 34 patients had normal ESR (J20 mm/h) and 33 patients had high ESR (>20 mm/h). Total arterial compliance was estimated by the ratio of echocardiographic (Teichholz) stroke volume to pulse pressure (SV/PP ratio). Patients with high ESR had lower SV/PP ratio than those with normal ESR (0.92±0.31 vs 1.2+0.48 ml/mmHg, respectively, p=0.006). The multiple regression analysis showed that ESR independent of the age, gender, body mass index, serum creatinine, serum albumin, hemoglobin was negatively related to SV/PP ratio (Multiple R 2 = 0.70; b=-40; p=0.02). These results suggest that low total compliance is associated with the inflammation with high ESR in pre-dialysis patients.

About the Authors

A. M. Shutov
Ульяновский государственный университет, Центральная городская клиническая больница, Областная клиническая больница
Russian Federation


N. I. Kondratieva
Ульяновский государственный университет, Центральная городская клиническая больница, Областная клиническая больница
Russian Federation


V. P. Mukhorin
Ульяновский государственный университет, Центральная городская клиническая больница, Областная клиническая больница
Russian Federation


T. H. Ivashkin
Ульяновский государственный университет, Центральная городская клиническая больница, Областная клиническая больница
Russian Federation


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For citations:


Shutov A.M., Kondratieva N.I., Mukhorin V.P., Ivashkin T.H. ERYTHROCYTE SEDIMENTATION RATE AND ARTERIAL COMPLIANCE IN PRE-DIALYSIS PATIENTS. Nephrology (Saint-Petersburg). 2003;7(1):62-66. (In Russ.) https://doi.org/10.24884/1561-6274-2003-7-1-62-66

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