МОДУЛЯТОРЫ ОКСАЛАТНОГО НЕФРОЛИТИАЗА. ИНГИБИТОРЫ КРИСТАЛЛИЗАЦИИ
https://doi.org/10.24884/1561-6274-2010-14-1-29-49
Аннотация
Обзор литературы посвящен описанию факторов, препятствующих нуклеации, агрегации и росту кристаллов оксалата кальция. Основными белковыми макромолекулами, ингибирующими образование почечных камней, являются протеин Тамма-Хорсфалла, остеопонтин, бикунин и фрагмент 1 протромбина. В обзоре анализируются особенности структуры и функции данных гликопротеинов, обсуждаются их вероятные механизмы действия и роль в патогенезе мочекаменной болезни.
Об авторах
Я. Ф. Зверев
Алтайский государственный медицинский университет, г. Барнаул
Россия
Россия
кафедра фармакологии
656038, г.Барнаул, пр.Ленина, 40, тел. (3852) 26-08-35
А. Ю. Жариков
Алтайский государственный медицинский университет, г. Барнаул
Россия
Россия
кафедра фармакологии
В. М. Брюханов
Алтайский государственный медицинский университет, г. Барнаул
Россия
Россия
кафедра фармакологии
В. В. Лампатов
Алтайский государственный медицинский университет, г. Барнаул
Россия
Россия
кафедра фармакологии
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Рецензия
Для цитирования:
Зверев Я.Ф., Жариков А.Ю., Брюханов В.М., Лампатов В.В. МОДУЛЯТОРЫ ОКСАЛАТНОГО НЕФРОЛИТИАЗА. ИНГИБИТОРЫ КРИСТАЛЛИЗАЦИИ. Нефрология. 2010;14(1):29-49. https://doi.org/10.24884/1561-6274-2010-14-1-29-49
For citation:
Zverev Ya.F., Zharikov A.Yu., Brukhanov V.M., Lampatov V.V. MODULATORS OF OXALATE NEPHROLITHIASIS. INHIBITORS’ CRYSTALLIZATION. Nephrology (Saint-Petersburg). 2010;14(1):29-49. (In Russ.) https://doi.org/10.24884/1561-6274-2010-14-1-29-49
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