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EXPERIENCE OF SUSTAINED LOW EFFICIENCY DIALYSIS (SLED) - METHODS RENAL REPLACEMENT THERAPY IN TREATMENT CARDIORENAL SYNDROME WITH DIURETIC-REFRACTORY EDEMAS

https://doi.org/10.24884/1561-6274-2010-14-1-63-67

Abstract

THE AIM. To evaluate an efficiency and safety of SLED-HF/HDF (hybrid methods of renal replacement therapy) in patients with congestive heart failure and refractory volume overload. PATIENTS AND METHODS. Fourteen patients with acute decompensated heart failure and acute volume overload and diuretic-refractory edemas were given SLED-HF/HDF before and after cardiac surgery. Parametrs SLED-HF/HDF including: fluid removal 2457±128 ml during procedure, using low dialysatе flow and acetate-free dialysatе («Krebsol»). RESULTS. Edemas’ and volume overloads regression, improvement of central and pulmonal hemodynamic and renal dysfunctions were achieved in 13 patients. CONCLUSION. Adapted parameters SLED-therapy including on-line blood volume monitoring, using low dialysatе flow (6 l/hour), acetate-free dialysatе («Krebsol») allowed to reduce complications (hypothensia and arrhythmia).

About the Authors

T. V. Mukhoedova
Новосибирский научно-исследовательский инсти­тут патологии кровообращения им. акад. Е.Н.Мешалкина
Russian Federation


Z. M. Unarokov
Новосибирский научно-исследовательский инсти­тут патологии кровообращения им. акад. Е.Н.Мешалкина
Russian Federation


References

1. Clark WR, Paganini E, Weinstein D et al. Report from the Acute Dialysis Quality Initiative. Int J Artif Organs. 2005; 28 (5)

2. Cadnapaphornchai MA, Gurevich AK, Weinberger HD et al. Pathophysiology of sodium and water retention in heart failure. Cardiology. 2001; 96:122-131

3. Boerigter G, Burnet JC. Cardiorenal syndrome in decompensated heart failure: prognostic and therapeutic implications. Curr Heart Fail Rep 2004; 1(3): 113-120

4. Ronco C, Chionh С-Y, Haapio M et al. The Cardiorenal Syndrome. Blood Purif 2009; 27: 114-126

5. Henderson LW, Besarab A, Michaelis A et al. Blood purification by ultrafiltration and fluid replacement (diafiltration). Trans Am Soc Artif Intern Organs 1967; 13: 216-226

6. Silverstein ME, Ford CA, Lysaght MT et al. Treatment of severe fluid overload by ultrafiltratin. N Engl J Med 1974; 291: 747-751

7. Magilligan DJ. Indications for ultrafiltration in the cardiac surgical patient. J Thorac Cardiovasc Surg1985; 89(2): 183-189

8. Ronco C, Ricci Z, Bellomo R et al. Extracorporeal ultrafiltration for the treatment of overhydration and congestive heart failure. Cardiology 2001; 96: 155-168

9. Libetta C, Sepe V, Zucchi M et al. Intermittent haemodiafiltration in refractory congestive heart failure: BNPand balance of inflammatory cytokines. Nephrol Dial Transplant 2007; 22 (7): 2013-2019

10. Canaud B, Leblanc M, Leray-Moragues H et al. Slow continuous and daily ultrafiltration for refractory congestive heart failure. Nephrol Dial Transplant 1998; 13 (Suppl 4): 51-55

11. Mehta RL. Fluid management in CRRT. Contrib Nephrol 2001; 132: 335-348

12. Ronco C, Bellomo R, Ricci Z. Hemodinamic response to fluid withdrawal in overhydratet patients treated with intermitten ultrafiltration and slow continuos ultrafiltration: role of blood volume monitoring. Cardiology 2001; 96: 196-201

13. Osabohien DS. Renal ultrafiltration (UF) for heart failure (HF). Blood Purif 2008; 26(5): 447

14. Dahle TG, Blake D, Ali SS et al. Large volume ultrafiltration for acute decompensated heart failure using standard peripheral intravenous catheters. J Card Fail 2006; 12(5): 349-352

15. Liang KV, Hinicer AR, Williams AW et al. Use of a novel ultrafiltration device as a treatment strategy for diuretic resistant, refractory heart failure: initial clinical experience in a single center. J Card Fail 2006; 12(9): 707-714

16. Tolwani AJ, Wheeler TS, Wille KM. Sustained Low- Efficiency Dialysis. In: C. Ronco, R. Bellomo, JA. Kellum eds: Acute Kidney Injury. Contrib Nephrol. Basel, Karger, 2007; 156: 320–324

17. Marenzi G, Agostoni P. Hemofiltration in heart failure. Int J Artif Organs 2004; 27(12): 1070-1076

18. Ronco C, Ricci Z. Renal replacement therapies: physiological review. Intensive Care Med 2008; 38: 2139-2146

19. Marenzi G, Lauri G, Grazi M et al. Circulatory response to fluid overload removal by extracorporeal ultrafiltration in refractory congestive heart failure. J Am Coll Cardiol 2001; 38: 963-968

20. Dileo M, Pacitti A, Bergeron S et al. Ultrafiltration in the treatment of refractory congestive heart failure. Clin Cardiol 1988; 11/7: 449-452

21. Costanzo MR, Saltsberg M, O’Sullivan J, Sobotka P. Early ultrafiltration in patients with decompensated heart failure and diuretic resistance. J AM Coll Card 2005; 46(11): 2047-2051

22. Fournier G, Potier J, Thebaud H-E et al. Substitution of acetic acid for hydrcloric acid in the bicarbonate buffered dialysate. Intern Soc for Artifical Org 1998; 22(7): 608-613

23. Pizzarelli F, Cerrai T, Dattolo P et al. On-line haemdiafiltration with and without acetate. Nephrol Dial Transplant 2006; 21(6):1648-1651

24. Naka T, Baldwin I, Bellomo R et al. Prolonged daily intermittent renal replacement therapy in ICU patients by ICU nurses and ICU physicians. Int J Artif Organs 2004; 27(5): 380-387

25. Yegenaga I, Vanholder R, Hoste E et al. Studу of hemodynamic disturbances during slow extended daily hemodialysis vs continuous renal replacement therapy in acute renal failure patients in the intensive care unit. Blood Purif 2004; 22: 240-241

26. Lima EQ, Fernandes A, Zanon J et al. Preventing intradialytic hypotension in acute kidney ingury patients submitted to slow low efficiency dialysis (SLED). Blood Purif 2008; 26: 179-180


Review

For citations:


Mukhoedova T.V., Unarokov Z.M. EXPERIENCE OF SUSTAINED LOW EFFICIENCY DIALYSIS (SLED) - METHODS RENAL REPLACEMENT THERAPY IN TREATMENT CARDIORENAL SYNDROME WITH DIURETIC-REFRACTORY EDEMAS. Nephrology (Saint-Petersburg). 2010;14(1):63-67. (In Russ.) https://doi.org/10.24884/1561-6274-2010-14-1-63-67

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ISSN 1561-6274 (Print)
ISSN 2541-9439 (Online)