АУТОСОМНО-ДОМИНАНТНЫЙ ПОЛИКИСТОЗ ПОЧЕК У ВЗРОСЛЫХ И ДЕТЕЙ
https://doi.org/10.24884/1561-6274-2010-14-3-58-68
Аннотация
Данный обзор является обобщением современных представлений о генетике, механизмах развития, клинике, диагностике аутосомно-доминантного поликистоза почек (АДПП). Представлены количественная и качественная характеристика мутаций в генах, ответственных за развитие заболевания, новейшие критерии УЗИ-диагностики АДПП, препараты для патогенетической терапии АДПП, которые проходят III фазу контролируемых клинических исследований.
Об авторах
С. С. Арутюнян
Санкт-Петербургская государственная педиатрическая медицинская академия
Россия
кафедра факультетской педиатрии
Россия
кафедра факультетской педиатрии
Н. Д. Савенкова
Санкт-Петербургская государственная педиатрическая медицинская академия
Россия
Россия
кафедра факультетской педиатрии
Санкт-Петербург, ул. Литовская, д. 2.
В. И. Ларионова
Санкт-Петербургская государственная педиатрическая медицинская академия
Россия
Россия
лаборатория молекулярной диагностики с расширенной группой по экогенетике Научно-исследовательского центра
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Рецензия
Для цитирования:
Арутюнян С.С., Савенкова Н.Д., Ларионова В.И. АУТОСОМНО-ДОМИНАНТНЫЙ ПОЛИКИСТОЗ ПОЧЕК У ВЗРОСЛЫХ И ДЕТЕЙ. Нефрология. 2010;14(3):58-68. https://doi.org/10.24884/1561-6274-2010-14-3-58-68
For citation:
Arutyunyan S.S., Savenkova N.D., Larionova V.I. AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE IN CHILDREN AND ADULTS. Nephrology (Saint-Petersburg). 2010;14(3):58-68. (In Russ.) https://doi.org/10.24884/1561-6274-2010-14-3-58-68
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