AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE IN CHILDREN AND ADULTS
https://doi.org/10.24884/1561-6274-2010-14-3-58-68
Abstract
This review is a conclusion of up-to-date conceptions about genetics, mechanisms of development, clinical features and diagnostics of autosomal dominant polycystic kidney disease (ADPKD). The quantitative and qualitative description of mutations in causative genes, novel criteria for ultrasound diagnostics of ADPKD and agents for pathogenetic therapy of ADPKD, which are under phase III controlled clinical trials are presented.
About the Authors
S. S. Arutyunyan
Санкт-Петербургская государственная педиатрическая медицинская академия
Russian Federation
Russian Federation
N. D. Savenkova
Санкт-Петербургская государственная педиатрическая медицинская академия
Russian Federation
Russian Federation
V. I. Larionova
Санкт-Петербургская государственная педиатрическая медицинская академия
Russian Federation
Russian Federation
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Review
For citations:
Arutyunyan S.S., Savenkova N.D., Larionova V.I. AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE IN CHILDREN AND ADULTS. Nephrology (Saint-Petersburg). 2010;14(3):58-68. (In Russ.) https://doi.org/10.24884/1561-6274-2010-14-3-58-68
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