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Stumbling blocks in kidney physiology and their overcoming
https://doi.org/10.36485/1561-6274-2026-30-1-9-19
EDN: BBJBOO
Abstract
Renal physiology is one of the fundamental branches of nephrology. It encompasses a number of complex issues that require discussion and consensus within the nephrology community. These include the question of partial renal functions, obligate reabsorption in the proximal tubule, key transformations in the kidney during its evolution, and their significance for human adaptation in pathological conditions. This article substantiates controversial terms and provides a modern understanding of the kidney's main functions. It outlines the mechanisms underlying urine formation and explains why they operate as they do. This relates to the enormous arterial blood flow of the kidneys, the mechanism of regulation of obligate proximal reabsorption, the replacement of the renal renoportal system with a higher arterial blood supply, and the importance of the kidneys in human homeostasis.
About the Author
Yu. V. Natochin
Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences
Russian Federation
Russian Federation
Academician of the Russian Academy of Sciences, Professor, Yuri Viktorovich Natochin
194223, St. Petersburg, Torez Ave. 44
Tel. (812)5523086
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Review
For citations:
Natochin Yu.V. Stumbling blocks in kidney physiology and their overcoming. Nephrology (Saint-Petersburg). 2026;30(1):9-19. (In Russ.) https://doi.org/10.36485/1561-6274-2026-30-1-9-19. EDN: BBJBOO
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