DEVELOPMENT OF CHRONIC KIDNEY DISEASE IN WOMEN WITH CHRONIC SARCOIDOSIS
https://doi.org/10.24884/1561-6274-2018-22-2-68-73
Abstract
THE AIM: to study the frequency of CKD in women suffering from chronic sarcoidosis. PATIENTS AND METHODS: 160 female patients with sarcoidosis without signs of primary renal pathology and severe cardiovascular pathology were divided into 3 groups depending on the activity of the disease: 1 – chronic progressive sarcoidosis, 2 – chronic sarcoidosis in remission 6-12 months, 3 – chronic sarcoidosis in remission more than 14 months. RESULTS: The negative effect of the progression of sarcoidosis on GFR was revealed. The lowest rGFR and the highest albuminuria were observed in the group of patients with progressive sarcoidosis, a reliable correlation was obtained between the progression of pulmonary fibrosis and renal markers of CKD. CONCLUSION: Progression of chronic sarcoidosis leads to a decrease in kidney function and the formation of chronic kidney disease.
About the Authors
M. V. Lebedeva
I.M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Marina V. Lebedeva, MD, Ph.D., Assistant professor, Faculty of Preventive Medicine, Department of Internal, Occupational diseases and pulmonology
119435, Moscow, Rossolimo str., 11/5
V. I. Sholomova
I.M. Sechenov First Moscow State Medical University;
Moscow State University. n.a.M.V. Lomonosov
Russian Federation
Russian Federation
Victoria I. Sholomova, MD, LomonosovMoscowStateUniversity, Faculty of Base Medicine, Department of Internal Medicine;I.M.Sechenov First Moscow State MedicalUniversity, Faculty of Preventive Medicine, Department of Internal, Occupational diseases and pulmonology; 3rd University Clinic, Department of pulmonology and occupational diseases.
119435, Moscow, Rossolimo str., 11/5
V. D. Beketov
I.M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Vladimir D. Beketov, MD, Faculty of Preventive Medicine, Department of Internal, Occupational diseases and pulmonology; 3rd University Clinic, Department of pulmonology and occupational diseases
119435, Moscow, Rossolimo str., 11/5
L. A. Strizhakov
I.M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Leonid A. Strizhakov, MD, PhD, DMedSci, Prof., Faculty of Preventive Medicine, Department of Internal, Occupational diseases and pulmonology; 3rd University Clinic, Department of pulmonology and occupational diseases
119435, Moscow, Rossolimo str., 11/5
M. V. Taranova
I.M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Marina V. Taranova, MD, PhD, Assistant professor, Faculty of Preventive Medicine, Department of Internal, Occupational diseases and pulmonology; 3rd University Clinic, Department of pulmonology and occupational diseases
119435, Moscow, Rossolimo str., 11/5
M. Yu. Brovko
I.M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Mikhail Yu. Brovko, 3rd University Clinic, Department of pulmonology and occupational diseases
119435, Moscow, Rossolimo str., 11/5
A. G. Serova
I.M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Anna G. Serova, MD, interclinical immunological laboratory of the Centralized laboratory and diagnostic service, a doctor of clinical laboratory diagnostics
119435, Moscow, ul. B. Pirogovskaya, 2, building 4 «B»
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Review
For citations:
Lebedeva M.V., Sholomova V.I., Beketov V.D., Strizhakov L.A., Taranova M.V., Brovko M.Yu., Serova A.G. DEVELOPMENT OF CHRONIC KIDNEY DISEASE IN WOMEN WITH CHRONIC SARCOIDOSIS. Nephrology (Saint-Petersburg). 2018;22(2):68-73. (In Russ.) https://doi.org/10.24884/1561-6274-2018-22-2-68-73
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