PROGNOSTIC SIGNIFICANCE OF AN ASSESSMENT OF ADAPTIVE REACTIONS IN CHILDREN WITH PYELONEPHRITIS

Abstract

AIM OF THE STUDY is to examine body adaptive response to the dynamics of the complex treatment of pyelonephritis in children for predicting the risk of a possible relapse. PATIENTS AND METHODS. The results of a study of adaptive reactions in 210 children with pyelonephritis are presented in the article. Chemiluminescence serum, whole blood and urine tests, evaluation of adaptive reactions leukocyte count, crystallography of urine are used in this study. RESULTS. The results obtained demonstrate various versions of violations of the child’s adaptation to the active phase of microbial inflammation in the urinary system depending on the degree of disease activity. Restructuring adaptive response depending on disease activity decrease was observed. It was found long-term preservation of violations of adaptation in chronic pyelonephritis. The results led us to conclusion that physico-chemical properties of urine characterizes the state of the local adaptive-compensatory mechanisms of the urinary system. The prognostic significance of determining the adaptive capacity of the organism, as well as the physico-chemical properties of the urine are shown. CONCLUSION. It was found that a comprehensive evaluation of adaptive responses to general and local levels can predict the nature of the flow of pyelonephritis and conduct timely correction of these states for the prevention of a possible relapse.