МЕДИКАМЕНТОЗНОЕ ЛЕЧЕНИЕ БОЛЬНЫХ С НЕЙРОГЕННОЙ ГИПЕРАКТИВНОСТЬЮ МОЧЕВОГО ПУЗЫРЯ
Аннотация
Гиперактивность мочевого пузыря (ГАМП) является одной из наиболее частых дисфункций нижних мочевых путей и клинически проявляется императивными позывами, учащением мочеиспускания и ургентным недержанием мочи. Антихолинергические препараты являются основой терапии больных с нейрогенной ГАМП. Они увеличивают емкость мочевого пузыря, снижают внутрипузырное давление, уменьшают интенсивность симптоматики ГАМП. Больным с нейрогенной ГАМП часто требуется назначать дозы антихолинергических препаратов, существенно превышающие таковые при лечении пациентов с идиопатической ГАМП. Кроме того, возможно комбинированное применение нескольких антихолинергических препаратов. Неэффективность или плохая переносимость пероральной медикаментозной терапии является показанием к внутрипузырному введению нейротоксинов, в первую очередь, ботулинического токсина.
Об авторах
С.Х. Аль-Шукри
Санкт-Петербургский государственный медицинский университет им. акад. И.П.Павлова
Россия
Кафедра урологии
Россия
Кафедра урологии
И. В. Кузьмин
Санкт-Петербургский государственный медицинский университет им. акад. И.П.Павлова
Россия
Россия
Кафедра урологии
197022, Санкт-Петербург, ул. Льва Толстого, д. 17, тел. (812) 234-19-54
Е. Е. Лукина
Санкт-Петербургский государственный медицинский университет им. акад. И.П.Павлова
Россия
Кафедра урологии
Россия
Кафедра урологии
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Для цитирования:
Аль-Шукри С., Кузьмин И.В., Лукина Е.Е. МЕДИКАМЕНТОЗНОЕ ЛЕЧЕНИЕ БОЛЬНЫХ С НЕЙРОГЕННОЙ ГИПЕРАКТИВНОСТЬЮ МОЧЕВОГО ПУЗЫРЯ. Нефрология. 2012;16(1):57-62. https://doi.org/10.24884/1561-6274-2012-16-1-57-62
For citation:
Al-Shukri S., Kuzmin I.V., Lukina E.E. PHARMACEUTICAL TREATMENT OF PATIENTS WITH NEUROGENIC OVERACTIVE BLADDER. Nephrology (Saint-Petersburg). 2012;16(1):57-62. (In Russ.) https://doi.org/10.24884/1561-6274-2012-16-1-57-62
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