NEPHROLOGIST’S IMPRESSION OF ENDOPLASMATIC RETICULUM STRESS (TEXT 1)
https://doi.org/10.24884/1561-6274-2012-16-3/1-54-71
Abstract
Review provides data about endoplasmatic reticulum stress (ER-stress). Data about biological role of ER-stress, its causes, intracellular events which provide adaptive and proapoptotic biochemical cascades underlying UPR, ER-stress reaction and identifying fortune of cell which has been exposed to influence of this stress is given. Physiological and pathophysiological aspects of ER-stress are discussed, its connection with hypoxia, inflammation, oxidative stress. ER-stress role in pathogenesis of some diseases is observed.
About the Authors
Ya. F. Zverev
Алтайского государственного медицинского университета
Russian Federation
Russian Federation
V. M. Bruhanov
Алтайского государственного медицинского университета
Russian Federation
Russian Federation
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Review
For citations:
Zverev Ya.F., Bruhanov V.M. NEPHROLOGIST’S IMPRESSION OF ENDOPLASMATIC RETICULUM STRESS (TEXT 1). Nephrology (Saint-Petersburg). 2012;16(3/1):54-71. (In Russ.) https://doi.org/10.24884/1561-6274-2012-16-3/1-54-71
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