INCIDENCE AND PREVALENCE OF LATE STAGES OF CHRONIC KIDNEY DISEASE IN THE REPUBLIC OF TUVA

THE AIM of the investigation was to assess the incidence and prevalence of chronic kidney disease (CKD) of the IVV stage in the Republic of Tuva. PATIENTS AND METHODS. A population investigation was performed in the Republic of Tuva from 01.07.2003 through 30.06.2004 in order to determine the incidence and prevalence with the IVV stages of CKD. RESULTS. A prevalence of the IVV stage of CKD among the population of Tuva proved to be rather high and equaled 493 cases/mln. Incidence with the IVV stages of CKD was 206 patients/mln for the whole population and 277 patients/mln for the city of Kyzyl. The incidence and prevalence with the IVV stages of CKD (GFR<30 ml/min or substitution renal therapy) was somewhat greater in the city than in the rural area. The total number of patients given substitution renal therapy (98% hemodialysis) is126 patients/mln. CONCLUSION. The prevalence of marked stages of CKD among the population of the Republic of Tuva is rather high and comparable with the world tendencies. The incidence and prevalence of IVV stages of CKD in the region under study is sufficiently higher than in the European part of Russia. In the Republic of Tuva as well as in other subjects of the Russian Federation, further accumulation of resources of the nephrological service is necessary for the improvement of early detection, prophylactics, quality and volume of the conservative and substitution therapy of CKD.

1. Locatelli F, Del Vecchio L, Pozzoni P. The importance of early detection of chronic kidney disease. Nephrol Dial Transplant 2002; 17 [suppl 11]: 27

2. Moeller S, Gioberge S, Brown G. ESRD patients in 2001: Global overview of patients, treatment modalities and development trends. Nephrol Dial Transplant 2002; 17: 2071 2076

3. Locatelli F, Pozzoni P, Del Vecchio L. Epidemiology of chronic kidney disease in Italy: Possible therapeutical approaches. J Nephrol 2003; 16: 110

4. Locatelli F, Valderrabano F, Hoenich N et al. Progress in dialysis technology: membrane selection and patient outcome. Nephrol Dial Transplant 2000; 15: 11331139

5. Jones CA, Krolewski AS, Rogus J et al. Epidemic of end stage renal disease in people with diabetes in the United States population: do we know the cause? Kidney Int 2005; 67(5): 1684 1691

6. Mcclellan WM, Ramirez SPB, Jurkovitz C. Screening of chronic kidney disease: Unresolved question. J Am Soc Nephrol 2003; 14: S81S87

7. Atkins RC. The epidemiology of chronic kidney disease. Kidney Int 2005; 67 [suppl 94]: S14S18

8. Xue JL, Ma JZ, Louis TA, Collins AJ. Forecast of the number of patients with endstage renal disease in the United States to the year 2010. J Am Soc Nephrol 2001; 12: 27532758

9. United States Renal Data System. Annual data report, 2004

10. Бикбов БТ, Томилина НА. О состоянии заместитель ной терапии больных с хронической почечной недостаточ ностью в Российской Федерации в 2001 г. (Отчет по данным регистра Российского диализного общества). Нефрология и диализ 2004; 6 (1): 442

11. Флетчер Р, Флетчер С, Вагнер Э. Клиническая эпидемиология. Основы доказательной медицины. Медиа Сфера, М., 1998; 1352

12. Levey AS, Greene T, Kusek JW, Beck GJ. A simplified equation to predict glomerular filtration rate from serum creatinine. J Am Soc Nephrol 2000; 11: A0828 (abstr)

13. Добронравов ВА, Смирнов АВ, Драгунов СВ и др. Эпидемиология хронической болезни почек в Вологодской области. Нефрология 2004; 8 (1): 3641

14. Добронравов ВА, Смирнов АВ, Драгунов СВ и др. Эпидемиология хронической почечной недостаточности в СевероЗападном регионе России: на пути к созданию ре гистра хронической почечной болезни. Тер арх 2004; 76 (9): 5761

15. Jungers P, Chauveau P, DescampsLatscha B et al. Age and genderrelated incidence of chronic renal failure in a French urban area: a prospective epidemiologic study. Nephrol Dial Transplant 1996; 11:15421546

16. Feest TG, Mistry CD, Grimes DS et al. Incidence of advanced chronic renal failure and the need for end stage renal replacement treatment. Brit Med J 1990; 301: 897900

17. Berthoux F, Jones E, Gellert R et al. Epidemiological data of treated endstage renal failure in the European Union (EU) during the year 1995: report of the European Renal Association Registry and the National Registries. Nephrol Dial Transplant 1999; 14(10): 23322342

18. Locatelli F, D’Amico M, Cernevskis H et al. The epidemiology of endstage renal disease in the Baltic countries: an evolving picture. Nephrol Dial Transplant 2001; 16: 1338 1342

19. Rutkowski B. Changing pattern of endstage renal disease in central and eastern Europe. Nephrol Dial Transplant 2000; 15: 156 –160

20. Sarnak MJ, Levey AS. Cardiovascular disease and chronic renal disease: A new paradigm. Am J Kidney Dis 2000; 35 [suppl 1]: S117S131

21. К проблеме лечения терминальной хронической почечной недостаточности в России. Первые итоги работы по созданию Российского национального регистра замес тительной почечной терапии. Нефрология и диализ 1999; 1 (1): 7984

22. Смирнов АВ, Каюков ИГ, Есаян АМ и др. Превентив ный подход в современной нефрологии. Нефрология 2004; 8 (3): 714

23. Palmer AJ, Rodby RA. Health economic studies assessing irbesartan use in patients with hypertension, type 2 diabetes, and microalbuminuria. Kidney Int 2004; 66 [suppl 92]: S118—S120

24. Alexander CM, Lyle PA, Keane WF et al. Losartan and the United State costs of endstage renal disease by baseline albuminuria in patients with type 2 diabetes and nephropathy. Kidney Int 2004; 66 [suppl 92]: S115S117