THE NEW IN DIAGNOSTICS OF CHRONIC PYELONEPHRITIS IN GIRLS

THE AIM of the work was to study magnesium homeostasis and diurnal monitoring of arterial pressure in girls of juvenile age with different forms of chronic pyelonephritis. PATINTS AND METHODS. 126 girls of juvenile age were examined. Control group consisted of 55 girls, besides there were 49 girls with chronic secondary pyelonephritis in the stage of clinicolaboratory remission, and 22 girls with chronic secondary pyelonephritis at the stage of exacerbation. RESULTS. Patients with chronic pyelonephritis (CP) at the stage of clinicolaboratory remission at the stage of exacerbation had different deviations in magnesium metabolism as compared with the girls from the control group. Curves of magnesium diurnal excretion with urine in sick girls differed from those of the control group. The arterial pressure (AP) levels and pulse by the results of diurnal monitoring of AP (DMAP) in patients with different forms of pyelonephritis were within normal for this gender and age, but in certain periods of time reliably higher than in the control group. There appeared a reliable correlation between mean values of erythrocyte magnesium and AD in the group of patients with CP at the stage of clinicolaboratory remission as compared with healthy girls. CONCLUSION. It was found that reliably decreased erythrocyte magnesium in CP patients in the stage of clinicolaboratory remission may be considered as a criterion of chronization of the inflammatory process. The change of the shape of diurnal magnesium excretion with urine in patients with CP at the stage of clinico laboratory remission as compared with CP at the stage of exacerbation may be considered as a criterion of exacerbation of the inflammatory process. The changes revealed in studying magnesium homeostasis and DMAP in the group at the stage of clinico laboratory remission show that these patients should be included in the group of risk of the development of arterial hypertension.

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