THE CHEMICAL COMPONENTS OF THE CONCREMENTS IN CHRONIC CALCULOUS PYELONEPHRITIS

Abstract

THE AIM. Nephrolythiasis – is a chronic disease, which is characterized by the presence of concrements in the tissues or cameras of the kidneys. The formation of the calculi is a result of complex difficult substance exchange disorders. The most common are solid crystal like calculi, which are composed of organic and non-organic salts – urates, oxalates, phosphates, carbonates, cystin, ksantin, etc. Nephrolythiasis is often concomitant with inflammation of renal tissue and system. So we thought reasonable to study the chemical components of the concrements in chronic calculous nephrolythiasis. PATIENTS AND METHODS. 584 patients, living in Varna area (Bulgaria), with examination at the St. Martin Hospital of the Medical University of Prof. Paraskev Stoyanov during the six years with the main or concomitant diagnosis of calculous pyelonephritis were investigated. The chemical components of the concrements were defined with the use of the «Urinary calculi analysis», Merk USA test. RESULTS. Pure oxalate calculi were discovered in 39 cases, pure phosphate in 34 cases. The combine concrements were noted in 443 patents. With that the calculi, which consisted of calcium oxalate with the phosphate mixture were noted in 175 patients, calcium oxalate with the urate mixture in 152 and calcium oxalate with carbonate mixture in 94 patients. CONCLUSION. The determination of the chemical compounds of the renal calculi is very important in the context of modern tendencies of preventive medicine