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CHRONIC KIDNEY DISEASE INFLUENCE ON PROGNOSIS AND READMISSION COST IN PATIENTS WITH CHRONIC HEART FAILURE

https://doi.org/10.24884/1561-6274-2010-14-2-51-55

Abstract

THE AIM. To study the effects of chronic kidney disease (CKD) on prognosis, as well as the frequency, duration of hospitalization and direct medical costs on inpatient care for patients with chronic heart failure (CHF). PATIENTS AND METHODS. The study involved 308 patients with CHF (men – 167, women – 141, mean age – 57. ±10.8 years) during observation period of 60 months. The main cause of CHF was the combination of ischemic heart disease and arterial hypertension – in 193 (63%) patients. The first functional class (FC) was diagnosed in 86.2 FC – at 180.3 FC - in 37, 4 FC – in 5 patients. 47 (15.4%) patients had diabetes. RESULTS. CKD with GFR <60 ml/min/1.73 m² was observed in 108 (35.1%) patients with CHF. The presence of CKD has led to an increase in mortality from all the reasons (relative risk 1.7), increase in average annual number of hospital-governmental organizations in one patient with chronic heart failure for any reason (0.9 [CI 95% 0.2-4.2] against 0.7 [CI 95% 0,09-2.5], p <0.02), and in connection with the aggravation of cardiovascular disease - (0.9 [CI 95% 0.6-5.2] against 0.6 [CI 95% 0.1-3.0], p <0.02). In the presence of CKD with GFR <60 ml/min/1, 73 m² cost of hospital treatment of patients with CHF increased by 21%. CONCLUSION. The presence of CHF patients with chronic kidney disease leads to increased mortality from all causes, increases the number of hospitalizations, duration and cost of hospitalizations for all causes in connection with the escalation cardiovascular disease.

About the Authors

E. R. Makeeva
Ульяновский государственный университет, г. Ульяновск
Russian Federation


A. M. Shutov
Ульяновский государственный университет, г. Ульяновск
Russian Federation


V. A. Serov
Ульяновский государственный университет, г. Ульяновск
Russian Federation


O. V. Troshenkina
Ульяновский государственный университет, г. Ульяновск
Russian Federation


S. V. Hiteva
Ульяновский государственный университет, г. Ульяновск
Russian Federation


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Review

For citations:


Makeeva E.R., Shutov A.M., Serov V.A., Troshenkina O.V., Hiteva S.V. CHRONIC KIDNEY DISEASE INFLUENCE ON PROGNOSIS AND READMISSION COST IN PATIENTS WITH CHRONIC HEART FAILURE. Nephrology (Saint-Petersburg). 2010;14(2):51-55. (In Russ.) https://doi.org/10.24884/1561-6274-2010-14-2-51-55

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ISSN 1561-6274 (Print)
ISSN 2541-9439 (Online)