Prediction reducing the glomerular filtration rate of the kidneys in patients with CAD in the long term after coronary revascularization
Abstract
THE AIM: to assess interactions between risk factors as well as arterial sclerotic bed lesion features and GFR decrease in patients with CHD in long term period after myocardial revascularization. PATIENTS AND METHODS. The study included 90 patients with CHD and indications for myocardial revascularization. All patients performed coronary angiography with subsequent surgical myocardial revascularization method definition. Traditional cardiovascular and renal risk factors (GFR) were analyzed in view of coronary angiography. 5,8 ± 0,05 years after blood flow recovery 52 patients were observed, some patients with GFR decrease were revealed. RESULTS. Significant effect of effort angina class III, left ventricular hypertrophy, left coronary artery (LCA) arterial sclerotic disease and also number of clinically significant and subtotal coronary artery stenosis on GFR decrease probability in long term after myocardial revascularization was established. Effort angina class III significantly increased the risk of GFR decrease by 38.2%, LVH - by 74.3%, atherosclerosis - by 40%. Table of calculated GFR aggravation risk stratification according to clinically significant and subtotal CA stenosis is presented. CONCLUSION. GFR factor before myocardial revascularization in patients with CHD is important risk factor of kidneys dysfunction progress in long term period.
About the Authors
E. S. Levickaja
Rostov State Medical University
Russian Federation
Russian Federation
M. M. Batiushin
Rostov State Medical University
Russian Federation
Russian Federation
E. O. Lafisheva
Rostov State Medical University
Russian Federation
Russian Federation
A. A. Kastanajan
Rostov State Medical University
Russian Federation
Russian Federation
A. V. Hripun
Rostov State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Levickaja E.S., Batiushin M.M., Lafisheva E.O., Kastanajan A.A., Hripun A.V. Prediction reducing the glomerular filtration rate of the kidneys in patients with CAD in the long term after coronary revascularization. Nephrology (Saint-Petersburg). 2015;19(5):42-48. (In Russ.)
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