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Cardio-vascular oalcification risk prognosis in patients receiving chronic hemodialysis

Abstract

THE AIM: to identify risk factors of cardiovascular calcification and to determine relationship between severity of valvular and vascular calcification in patients with S5d CKD. PATIENTS AND METHODS: The study involved 83 patients of two outpatient hemodialysis centers. In all patients studied medical history, anthropometric and laboratory data. We analyzed results of instrumental methods, including heart echocardiography and abdominal plain film in the lateral projection. RESULTS: Positive correlation between severity of heart valve calcification as assessed by echocardiography, and degree of aortic calcification according to survey abdominal radiography (r = 0,301, p = 0,006). Revealed malnutrition and inflammation importance in extraossal calcification development. At lower total protein (χ2=8,97, р=0,003), lower level of albumin (χ2=13,9, р<0,01) and increasing of pulse blood pressure (χ2=5,9, р=0,01) cardiovascular calcification formation possibility increased. calcification risk increase occurs not only with pulse pressure increase, but also in hypertension development (χ2=10,6, р=0,005). CONCLUSION: Thus, the severity of valvular calcification associated with aorta calcification, role of malnutrition, inflammation and calcium-phosphorus homeostasis disorders in extraossal calcification development is established.

About the Authors

L. I. Rudenko
Rostov State Medical University
Russian Federation


M. M. Batiushin
Rostov State Medical University
Russian Federation


A. A. Kastanayan
Rostov State Medical University
Russian Federation


B. I. Vorobiev
Rostov State Medical University
Russian Federation


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Review

For citations:


Rudenko L.I., Batiushin M.M., Kastanayan A.A., Vorobiev B.I. Cardio-vascular oalcification risk prognosis in patients receiving chronic hemodialysis. Nephrology (Saint-Petersburg). 2015;19(5):72-76. (In Russ.)

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ISSN 1561-6274 (Print)
ISSN 2541-9439 (Online)