MODERN APPROACHES TO THE DIAGNOSIS AND TREATMENT OF RENAL DISEASE IN CHILDREN
https://doi.org/10.24884/1561-6274-2018-22-3-72-87
Abstract
Microbial-inflammatory diseases of the urinary system are one of the most pressing health and social problems. Currently, there is an increase in the frequency of progressive forms of urinary tract infection in childhood and adolescence. Up to the present time remains the issue of criteria for early diagnosis of renal infection, sources of infection, verification of the source of the causative agent of pyelonephritis, mechanisms of formation and progression of IMS, and the basic treatment of pyelonephritis. Advances in the diagnosis and treatment of pyelonephritis is significantly associated with the depth and precision of knowledge about the etiology and mechanisms of development of renal infection. The article presents modern data on the etiology and pathogenetic mechanisms of forming renal infection in children. Described clinical features of urinary tract infection. Discussed diagnostic criteria, based on data of complex studies to confirm the source of infection of the urinary system and structural-functional criteria changes tubulo-interstitium of kidney with involvement of the Cup-pelvis-plating system, blood and lymph vessels of the kidneys. Proposed etiologic approach to diagnosis and treatment, taking into account the pathogenetic mechanisms of the formation of IMS and morpho-functional approach to the prediction of the flow and the choice of tactics of management of children with renal infection.
About the Authors
A. A. Vyalkova
Endocrinology of Orenburg State Medical University
Russian Federation
MD, PhD, DMedSci, Orenburg State Medical University, Head of Department of faculty Pediatrics, Endocrinology
Russian Federation
MD, PhD, DMedSci, Orenburg State Medical University, Head of Department of faculty Pediatrics, Endocrinology
V. A. Gritsenko
Institute of Cellular and Intracellular Symbiosis Ural Branch of the Russian Academy of Sciences, Orenburg
Russian Federation
Professor Gritsenko Victor Alexandrovich MD, PhD, DMedSci. Institute of Cellular and Intracellular Symbiosis, Ural Division of the Russian Academy of Sciences, Head of the Laboratory of Cellular Symbiosis
Russian Federation
Professor Gritsenko Victor Alexandrovich MD, PhD, DMedSci. Institute of Cellular and Intracellular Symbiosis, Ural Division of the Russian Academy of Sciences, Head of the Laboratory of Cellular Symbiosis
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Review
For citations:
Vyalkova A.A., Gritsenko V.A. MODERN APPROACHES TO THE DIAGNOSIS AND TREATMENT OF RENAL DISEASE IN CHILDREN. Nephrology (Saint-Petersburg). 2018;22(3):72-87. (In Russ.) https://doi.org/10.24884/1561-6274-2018-22-3-72-87
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