MYH9-ASSOCIATED SYNDROME EPSTEIN: MACROTHROMBOCYTOPENIA, SENSORINEURAL HEARING LOSS, NEPHROPATHY IN CHILDREN (ACCORDING TO THE LITERATURE)
https://doi.org/10.24884/1561-6274-2018-22-3-88-94
Abstract
The article presents literature data on clinical and morphological manifestations of MYH9-associated Epstein syndrome, flowing with macrothrombocytopenia, sensorineural hearing loss, nephropathy. The pathogenetic foundations, clinical features, course, treatment and prognosis of MYH9-associated Epstein syndrome in children are discussed. The paper presents clinical observation confirmed by molecular genetic study MYH9-associated Epstein syndrome in an 8-year-old boy.
About the Authors
O. P. Grigoreva
Saint-Petersburg State Pediatric Medical University
Russian Federation
MD, PhD, SaintPetersburg State Pediatric Medical University Assistant of the department of faculty pediatric
Russian Federation
MD, PhD, SaintPetersburg State Pediatric Medical University Assistant of the department of faculty pediatric
N. D. Savenkova
Saint-Petersburg State Pediatric Medical University
Russian Federation
Prof., MD, PhD, DMedSci, Saint-Petersburg State Pediatric Medical University Head of the department of faculty pediatric
Russian Federation
Prof., MD, PhD, DMedSci, Saint-Petersburg State Pediatric Medical University Head of the department of faculty pediatric
K. A. Papayan
Saint-Petersburg State Pediatric Medical University
Russian Federation
Associate professor, MD, PhD, DMedSci, SaintPetersburg State Pediatric Medical University, department Faculty pediatrics
Russian Federation
Associate professor, MD, PhD, DMedSci, SaintPetersburg State Pediatric Medical University, department Faculty pediatrics
N. Y. Natochina
Saint-Petersburg State Pediatric Medical University
Russian Federation
Associate professor, MD, PhD, SaintPetersburg State Pediatric Medical University, department Faculty pediatrics
Russian Federation
Associate professor, MD, PhD, SaintPetersburg State Pediatric Medical University, department Faculty pediatrics
V. M. Sidorenko
Saint-Petersburg State Pediatric Medical University
Russian Federation
student
Russian Federation
student
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Review
For citations:
Grigoreva O.P., Savenkova N.D., Papayan K.A., Natochina N.Y., Sidorenko V.M. MYH9-ASSOCIATED SYNDROME EPSTEIN: MACROTHROMBOCYTOPENIA, SENSORINEURAL HEARING LOSS, NEPHROPATHY IN CHILDREN (ACCORDING TO THE LITERATURE). Nephrology (Saint-Petersburg). 2018;22(3):88-94. (In Russ.) https://doi.org/10.24884/1561-6274-2018-22-3-88-94
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