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ИНТЕРАКТОМИКА – АНАЛИТИЧЕСКИЙ ИНСТРУМЕНТ ДЛЯ ИЗУЧЕНИЯ МОЛЕКУЛЯРНЫХ ОСНОВ НЕФРОПАТИЙ

https://doi.org/10.24884/1561-6274-2013-17-5-9-15

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Аннотация

Сегодня появилась возможность изучать клеточные процессы с помощью нового инструмента – интерактомики – области биоинформатики и системной биологии, идея которой заключается в объединении данных молекулярных взаимодействий на уровнях от метаболома и до регуляции эпигенома в единые схемы. Объединение в одной аналитической системе свойств высокоинформативных маркерных клеточных и характеристик интерактомики, как технического воплощения системной биологии, позволило получить очень мощный инструмент для подробного изучения функционирования клеток различных тканей, в том числе и при развитии патологических процессов. С точки зрения нефрологии, интерактомика кажется многообещающим подходом для изучения молекулярных основ нефропатий и нарушений продукции почками эритропоэтина.

Об авторах

П. В. Золотухин
НИИ биологии, Южный федеральный университет
Россия
344090, г. Ростов-на-Дону, пр-т Стачки, д. 194/1. Факс: (863) 299-56-61, тел.: (863) 297-50-70


А. А. Александрова
НИИ биологии, Южный федеральный университет
Россия


А. Д. Довжик
Южный федеральный университет
Россия
факультет биологических наук


Ю. А. Лебедева
Южный федеральный университет
Россия
факультет биологических наук


О. Н. Кузьминова
Южный федеральный университет
Россия
факультет биологических наук


Л. В. Гутникова
НИИ биологии, Южный федеральный университет
Россия


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Для цитирования:


Золотухин П.В., Александрова А.А., Довжик А.Д., Лебедева Ю.А., Кузьминова О.Н., Гутникова Л.В. ИНТЕРАКТОМИКА – АНАЛИТИЧЕСКИЙ ИНСТРУМЕНТ ДЛЯ ИЗУЧЕНИЯ МОЛЕКУЛЯРНЫХ ОСНОВ НЕФРОПАТИЙ. Нефрология. 2013;17(5):9-15. https://doi.org/10.24884/1561-6274-2013-17-5-9-15

For citation:


Zolotukhin P.V., Aleksandrova A.A., Dovzhik A.D., Lebedeva U.A., Kuzminova O.N., Gutnikova L.V. INTERACTOMICS: A NOVEL ANALYTICAL INSTRUMENT FOR STUDYING THE MOLECULAR BASIS OF NEPHROPATHIES. Nephrology (Saint-Petersburg). 2013;17(5):9-15. (In Russ.) https://doi.org/10.24884/1561-6274-2013-17-5-9-15

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