USING OF NEW MARKER OF GLOMERULAR FILTRATION RATE EVALUATION – CYSTATIN C IN PEDIATRIC PATIENTS
https://doi.org/10.24884/1561-6274-2013-17-3-75-79
Abstract
This article discusses the possibility of using a new marker for the determination of renal function in pediatric patients - cystatin C. AIM OF STUDY: to determine the glomerular filtration rate using different methods of creatinine, as well as a new marker of kidney injury - cystatin C in children. PATIENTS AND METHODS: 83 patients from 1 month to 17 years (mean age 4,15 ± 5,08 years) with various nephropathies were examined. RESULTS: were determined the serum concentration of cystatin C (1,3 ± 0,38 mg/l), creatinine (0,62 ± 0,72 mg%) and glomerular filtration rate (GFR) using formulas based on creatinine and cystatin C. We conducted a comparative analysis of glomerular filtration with different methods of study. CONCLUSION: The serum concentration of cystatin C is independent of sex, and its higher level is determined in the first year of life. The most important for practical use in pediatrics are formulas using cystatin C and creatinine.
About the Authors
V. P. Sitnikova
ГБОУ ВПО «Воронежская государственная медицинская академия им. Н.Н. Бурденко» Минздрава России
Russian Federation
Russian Federation
Y. V. Pashkova
ГБОУ ВПО «Воронежская государственная медицинская академия им. Н.Н. Бурденко» Минздрава России
Russian Federation
Russian Federation
I. N. Popova
Воронежская областная детская клиническая больница №1
Russian Federation
Russian Federation
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Review
For citations:
Sitnikova V.P., Pashkova Y.V., Popova I.N. USING OF NEW MARKER OF GLOMERULAR FILTRATION RATE EVALUATION – CYSTATIN C IN PEDIATRIC PATIENTS. Nephrology (Saint-Petersburg). 2013;17(3):75-79. (In Russ.) https://doi.org/10.24884/1561-6274-2013-17-3-75-79
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