USING OF NEW MARKER OF GLOMERULAR FILTRATION RATE EVALUATION – CYSTATIN C IN PEDIATRIC PATIENTS
https://doi.org/10.24884/1561-6274-2013-17-3-75-79
Abstract
This article discusses the possibility of using a new marker for the determination of renal function in pediatric patients - cystatin C. AIM OF STUDY: to determine the glomerular filtration rate using different methods of creatinine, as well as a new marker of kidney injury - cystatin C in children. PATIENTS AND METHODS: 83 patients from 1 month to 17 years (mean age 4,15 ± 5,08 years) with various nephropathies were examined. RESULTS: were determined the serum concentration of cystatin C (1,3 ± 0,38 mg/l), creatinine (0,62 ± 0,72 mg%) and glomerular filtration rate (GFR) using formulas based on creatinine and cystatin C. We conducted a comparative analysis of glomerular filtration with different methods of study. CONCLUSION: The serum concentration of cystatin C is independent of sex, and its higher level is determined in the first year of life. The most important for practical use in pediatrics are formulas using cystatin C and creatinine.
About the Authors
V. P. SitnikovaRussian Federation
Y. V. Pashkova
Russian Federation
I. N. Popova
Russian Federation
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Review
For citations:
Sitnikova V.P., Pashkova Y.V., Popova I.N. USING OF NEW MARKER OF GLOMERULAR FILTRATION RATE EVALUATION – CYSTATIN C IN PEDIATRIC PATIENTS. Nephrology (Saint-Petersburg). 2013;17(3):75-79. (In Russ.) https://doi.org/10.24884/1561-6274-2013-17-3-75-79