Исследования эффективности цитостатической терапии часто рецидивирующего, гормонозависимого и со стероидной токсичностью нефротического синдрома у детей
Аннотация
В обзоре литературы обобщены имеющиеся данные контролируемых и ретроспективных исследований эффективности цитостатической терапии алкилирующими агентами, ингибиторами кальцинейрина и синтеза нуклеотидов часто рецидивирующего, гормонозависимого и со стероидной токсичностью нефротического синдрома у детей.
Ключевые слова
Об авторах
П. А. Ныркова
Санкт-Петербургский государственный педиатрический медицинский университет
Россия
Россия
Н. Д. Савенкова
Санкт-Петербургский государственный педиатрический медицинский университет
Россия
Россия
Список литературы
1. International Study of Kidney Disease in Children. The primary nephrotic syndrome in children. Identification of patients with minimal change nephrotic syndrome from initial response to prednisone. J Pediatr 1981; 98 (4): 561-564
2. APN Arbeitsgemeinschaft fur PadiatrischeNephrologie Short versus standart prednisolone therapy for initial treatment of idiopatic nephrotic syndrome in children. Lancet 1988;1: 380-383
3. Гринбаум Н.Б. Особенности нефротического синдрома у детей. В: Гломерулонефрит. Под ред. С.И. Рябова.- Л. 1980: 164-176 [Greenbaum NB. Osobennosti nefroticheskogo sindroma u detei'. V Glomerulonefrit. Pod red. S.I. Riabova.- L. 1980: 164-176]
4. Gbadegesin R, Smoyer W. Nephrotic Syndrome. In Comprehensive Pediatric Nephrology. Editors D. Geary, F. Schaefer. MOSBY 2008; 205-218
5. Hodson E, Alecsander S, and Graf N. Steroid-Sensitive Nephrotic Syndrome.In Comprehensive Pediatric Nephrology. Editors D.Geary, F. Schaefer. MOSBY 2008; 239-256
6. Arbeitsgemeinschaft fur PadiatrischeNephrologie: Minimal -change nephrotic syndrome (MCNS): long prednisone versus standard prednisone therapy (Abst) PediatrNephrol 1990; 4 :60
7. Niauted P. Steroid-Sensitive IdiopaticNephrotic Syndrome in Children.In Pediatric Nephrology. Editors E.Avner, W.Harmon, P.Niauted. LIPPINCOTT-WILLIAMS-WILKINS, 2004: 544-556
8. Niauted P, Boyer O. Idiopathic Nephrotic Syndrome in Children: Clinical Aspects. In Pediatric Nephrology, 6- th edition. Editors E. Avner, W.Harmon, N Yoshikawa.IPNA. Springer-Verlag, 2009; Vol.1:667-702
9. Brodehl J. Conventional therapy for idiopathic nephrotic syndrome in children. Clin. Nephrol1991; 35(1): 8-15
10. Савенкова Н.Д., Папаян А.В. Нефротический синдром в практике педиатра. С-Пб., Эскулап (1999): 256 [Savenkova ND, Papajan AV. Nefroticheskij sindrom v praktike pediatra. S-Pb., Jeskulap (1999): 256]
11. Батракова И.В., Савенкова Н.Д. Цитостатическая терапия нефротического синдрома с минимальными изменениями у детей. Нефрология 2004; 2:98-105 [Batrakova IV, Savenkova ND. Citostaticheskaja terapija nefroticheskogo sindroma s minimal’nymi izmenenijami u detej. Nefrologija 2004; 2:98-105]
12. Савенкова Н.Д., Папаян А.В., Батракова И.В. Нефротический синдром с минимальными изменениями у детей. В: Клиническая нефрология детского возраста. «Левша. Санкт-Петербург», 2008; 279-302 [Savenkova ND, Papajan AV, Batrakova IV. Nefroticheskij sindrom s minimal’nymi izmenenijami u detej. V Klinicheskaja nefrologija detskogo vozrasta. «Levsha. Sankt-Peterburg», 2008; 279-302]
13. Bargman JM. Management of minimal lesion glomerulonephritis Evidence-based recommendations. Kidney Int 1999; Suppl 70 (55): 3-16
14. Савенкова НД. Стратегия терапии дебюта, рецидивирующего и часто рецидивирующего гормоночувствительного и гормонозависимого нефротического синдрома с минимальными изменениями у детей. Нефрология 2013 №3: 17-25 [Savenkova ND. Strategija terapii debjuta, recidivirujushhego i chasto recidivirujushhego gormonochuvstvitel’nogo i gormonozavisimogo nefroticheskogo sindroma s minimal’nymi izmenenijami u detej. Nefrologija 2013 №3: 17-25]
15. Lombel RM, Hodson EM, Gipson DS. Treatment of steroid-resistant nephritic syndrome in children: new guidelines from KDIGO. Pediatr Nephrol2013 Mar;28(3):409-414
16. Clark A, Barratt TM. Steroid-responsive nephrotic syndrome. In Pediatric nephrology. Edited by ТМ. Barratt, E.D. Avner, WE Harman. LIPPINCOTT-WILLIAMS-WILKINS, 1998; 731-747
17. Pennisi AJ, Grushkin CM, Lieberman E. Cyclophosphamid in the treatment of idiopathic nephrotic syndrome. Pediatrics 1976; 57: 948-951
18. International Study of Kidney Disease in Children: Prospective, controlled trial of cyclophosphamide therapy in children with the nephrotic syndrome. Lancet 1974; 2: 423-427
19. Arbeitsgemeinschaft fur Padiatrische Nephrologie: Cyclophosphamide treatment of steroid dependent nephrotic syndrome: Comparison of eight week with 12 week course. Arch Dis Child 1987; 62: 1102-1106
20. Ueda N, Kuno K, Ito S. Eight and 12 week courses of cyclophosphamide in nephrotic syndrome. Arch Dis Child 1990; 85: 1147-1150
21. Ponticelli C, Edefonti A, Ghio L.Cyclosporin versus cyclophosphamide for patients with steroid dependent and frequently relapsing idiopathic nephrotic syndrome: a multicenter randomized controlled trial. Nephrol Dial Transplant 1993; 8: 1326-1332
22. Takeda A, Niimura F. Long-term effect of immunosuppressants in steroid-dependent nephrotic syndrome. PediatrNephrol 1998; 12 (9): 746-750
23. Kemper MJ, Altrogg H, Ludwig K et al. Unfavorable response to cyclophosphamide in steroid-dependent nephrotic syndrome. PediatrNephrol 2000; 14: 772-775
24. Vester U, Zimmermann S, Hoyer P. Cyclophosphamide therapy in frequent relapsing and steroid dependent minimal change nephrotic syndrome: new insights from an old protocol (abstract). PediatrNephrol 1999; 13: 67
25. Vester U, Kranz B, Zimmermann S, Hoyer P. Cyclophosphamide in frequently relapsing and steroid dependent nephrotic syndrome: Abstracts The 12 the Congress of the International Pediatric. NephrologyAssociationPediatrNephrol 2001; 16 (8): 258
26. Vester U, Kranz B. Cyclophosphamide in steroid-sensitive nephrotic syndrome outcome and outlook. PediatrNephrol. (2003) 18: 661-664
27. Kyrieleis HA, Levtcenko EN, Wetzels JF. Long-term outcome after cyclophosphamide treatment in children with steroid-dependent and frequently relapsing minimal change nephritic syndrome.Am J Kidney Dis 2007; 49:592-597
28. Sümegi V, Haszon I, Bereczki C, Papp F, Tûri S. Long-term follow-up after cyclophosphamide and cyclosporine-A therapy in steroid-dependent and -resistant nephrotic syndrome. Pediatr Nephrol 2008 Jul;23(7):1085-1092
29. Chen SY Wu CY Tsai IJ, Tsau YK. Treatment course of steroid-dependent nephrotic syndrome: emphasized on treatment effect. Nephrology (Carlton) 2010;15(3):336-339
30. Cammas B, Harambat J, Bertholet-Thomas A. et al. Long-term effects of cyclophosphamide therapy in steroid-dependent or frequently relapsing idiopathic nephrotic syndrome. Nephrol Dial Transplantant 2011; 26: 178-184
31. Zagury A, Louse A. et al. Long- term follow-up after cyclophosphamide therapy in steroid dependent nephrotic syndrome. Pediatr Nephro /2011; 26: 915-920
32. Azib S, Macher M, Kwon T et al. Cyclophosphamide in steroid dependent nephrotic syndrome. Pediatr Nephrol 2011; 26: 927-932
33. Grup W, Makker SP, Ingelfinger JR. Chlorambucil treatment of frequently relapsing nephrotic syndrome. N Engl J Med 1976; 295: 746-749
34. Niaudet P. Comparison of cyclosporin and chlorambucil in the treatment of steroid-dependent idiopathic nephrotic syndrome: a multicentre randomized controlled trial. The French Society of Paediatric Nephrology. PediatrNephrol 1992;6(1):1-3
35. Настаушева ТЛ, Ситникова ВП, Стеньшинская EB, Cтaxурлова ЛИ. Иммуносупрессивная терапия гломерулонефрита у детей цитостатическими препаратами алкилирующего действия. Нефрология и диализ 2000 2(4): 291-292 [Nastausheva TL, Sitnikova VP, Sten’shinskaja EB, Ctaxurlova LI. Immunosupressivnaja terapijaglomerulonefrita u detej citostaticheskimi preparatami alkilirujushhego dejstvija. Nefrologija i dializ 2000 2(4): 291-292]
36. Lewis MA, Baildom EM, Davis N, Houston IB, Postlethwaite RJ. Nephrotic syndrome: from toddlers to twenties. Lancet 1989 Feb 4;1(8632):255-259
37. Fakhouri F, Bocquet N, Taupin P. et al. Steroid-sensitive nephrotic syndrome: from childhood to adulthood. Am J Kidney Dis 2003 Mar;41(3):550-7
38. Rüth EM, Kemper MJ, Leumann EP. Et al. Children with steroid-sensitive nephrotic syndrome come of age: long-term outcome. J Pediatr 2005 Aug;147(2):202-7
39. Kyrieleis H, Löwik M, Pronk I. et al. Clin Long-Term Outcome of Biopsy-Proven, Frequently Relapsing Minimal-Change Nephrotic Syndrome in Children. J Am SocNephrol 2009; 4(10): 1593-1600
40. Kitano X Yoshikawa N, Tanaka R et al. Cyclosporin treatment in children with steroid-dependent nephrotic syndrome. Pediatr Nephrol 1990; 4: 474-477
41. Tanaka Н, Yoshikava N, Kitano Y: Long-term Cyclosporin treatment in children with steroid dependent nephrotic syndrome. Pediatr Nephrol 1993; 7: 249-252
42. Ponticelli C, Edefonti A, Ghio L. et al. Cyclosporin versus cyclophosphamide for patients with steroid dependent and frequently relapsing idiopathic nephrotic syndrome: a multicenter randomized controlled trial. Nephrol Dial Transplant 1993; 8: 1326-1332
43. Hulton SA, Neuhaus TJ, Dillon MJ, Barrat TM. Long-term cyclosporine A treatment of minimal-change nephrotic syndrome of children. Pediatr Nephrol 1994; 8: 401-403
44. Inou X Iijima K, Nakamura H, Yoshikava N: Two-year Cyclosporin treatment in children with steroid dependent nephrotic syndrome. Pediatr Nephrol 1999; 13: 33-38
45. Игнатова МС, Турпитко ОЮ, Харина ЕА, Обухова ВА. Результаты многоцентрового изучения эффективности циклоспорина А при нефротическом синдроме у детей. Педиатрия 2008; 87:93-97 [Ignatova MS, Turpitko OJu, Harina EA, Obuhova VA. Rezul’taty mnogocentrovogo izuchenija jeffektivnosti ciklosporina A pri nefroticheskom sindrome u detej. Pediatrija 2008; 87:93-97]
46. Dorresteijn EM, Kist-van Holthe JE, Levtchenko EN, Nauta J, Hop WC, van der Heijden AJ. Mycophenolate mofetil versus cyclosporine for remission maintenance in nephrotic syndrome. Pediatr Nephrol 2008; 23(11):2013-2020
47. Wang W, Xia XMao J. et al. Treatment of tacrolimus or cyclosporine A in children with idiopathic nephrotic syndrome. Pediatr Nephrol 2012; 27: 2073-2079
48. Tejani A, Butt K,TrechtmanH. Cyclosporin A induced remission of frequently relapsing nephrotic syndrome in children. Kidney Int1988; 33:729-734
49. Iijima K, Hamahira K, Tanaka R. et al. Risk factors for cyclosporine-induced tubulointerstitial lesions in children with minimal change nephrotic syndrome. Kidney Int 2002; 61(5):1801-1805
50. Rinaldi S, Sesto A, Barsotti P et al. Cyclosporine therapy monitored with abbreviated area under curve in nephrotic syndrome. Pediatr Nephrol 2005; 20: 25-29
51. Matsumoto H, Hakao T, Okada T et al. Initial remission inducing effect of very low-olosecyclosporin monotherapy for minimal-change nephrotic syndrome in Japannese adults. Clin. Nephrol2001; 55(2): 143-148
52. Fujinaga S, Kaneko K, Muto T. et al. Independent risk factors for chronic cyclosporine induced nephropathy in children with nephrotic syndrome. Arch Dis Child 2006; 91(8):666-670
53. Igarashi Y et al. Steroid-sparing effect of mizoribine in long-term nephrotic syndrome of children. PediatrNephrol 1994; 8: 396-397
54. Yoshioka K, Ohashi X Sacai T et al. A multicenter trial of mizoribine compared with placebo in children in frequently relapsing idiopathic nephrotic syndrome. Kidney Int 2000; 58: 317-324
55. Fujieda M, Ishihara M, Morita T. et al. Effect of oral mizoribine pulse therapy for frequently relapsing steroid-dependent nephrotic syndrome. ClinNephrol 2008; 69(3):179-184
56. Fujieda M, Ishihara M, Morita T. et al. Effect of singledose oral mizoribine pulse therapy twice per week for frequently relapsing steroid-dependent nephrotic syndrome. Clin Nephrol 2012;78(1):40-46
57. Fujinaga S, Hirano D, Nishizaki N. Single daily high-dose mizoribine therapy for children with steroid-dependent nephritic syndrome prior to cyclosporine administration. Pediatr Nephrol 2011; 26: 479-483
58. Kawasaki X Takano K, Isome M et al. Efficacy of single dose of oral mizoribine pulse therapy two times per week for frequently relapsing nephritic syndrome. J Nephrol 2007 20:52-56
59. Hogg R, Fizgibbons L, Bruick J et al. Multicenter trial of mycophenolate mofetil (MMF) in children with steroid dependent (SD) or frequently relapsing (FR) nephrotic syndrome (NS). Report of the southwest pediatric nephrology study group. Abstract book from the World Congress of Nephrology.June 8-12, Berlin (2003). Nephrol Dial Transplant 2003; 18 (Suppl. 4): 261
60. Barletta GM, Smoyer WE, BunchmannTE et al. Use of mycophenolate mofetil in steroid-dependent and-resistant nephrotic syndrome. Pediatr Nephrol 2003; 18:833-837
61. Vallejo GG, Liern MM, De Reyes VV et al. Enteric Coated Mycophenolate Sodium in Patients with steroid-dependent nephrotic syndrome. Congress Abstracts the 15th Congress of the International Pediatric Nephrology Association. August 29- September, 2010, New York. Pediatr Nephrol 2010; 25:1886
62. Bagga A, Hari P, Moudgil A, Jordan SC: Mycophenolate mofetil and prednisolone therapy in children with steroid-dependent nephritic syndrome. Am J Kidney Dis 2003;42: 1114-1120
63. Novak L, Frank R, Vento S et al. Efficacy of mycophenolate mofetil in pediatric patients with steroid-dependent nephrotic syndrome. Pediatr Nephrol 2005; 20(9) 1265-1268
64. Mendizabal S, Zamona I, Berbel O et al. Mycophenolate mofetil in steroid/cyclosporine-dependent/resistant nephrotic syndrome. Pediatr Nephrol 2005; 20(7):914-919
65. Kwinta-Rybicka J, Wilkosz K, Wierchowska-Slowiacze EK et al. Mycophenolate mofetil in treatment of childhood nephrotic syndrome -preliminary report. Przegl Lec 2006;63 Suppl 3:44-48
66. Fujinaga S, Ohtomo X Umino D. et al. A prospective study on the use of mycophenolate mofetil in children with cyclosporine-dependent nephrotic syndrome. Pediatr Nephrol 2007; 22: 71-76
67. Afzal K, Bagga A, Menon S et al. Treatment with mycophenolatemofetil and prednisolone for steroid-dependent nephritic syndrome. Pediatr Nephrol 2007; 22: 2059-2065
68. Nickavar A, Safarzadeh AE, Sotoudeh K et al. Mycophenolate mofetil for treatment of idiopathic nephrotic syndrome in children. Iran J Kidney Dis 2012; 6(5):346-349
69. Baudouin V, Albrti C, Lapeyraque AL et al. Mycophenolate mofetil for steroid-dependent nephrotic syndrome: a phase II Bayesian trial. Pediatr Nephrol 2012;27(3):389-396
70. Banerjee S, Pahari A, Sengupta J, Patnaik S. Outcome of severe steroid-dependent nephrotic syndrome treated with mycophenolate mofetil. Pediatr Nephrol 2013; 28:93-97
71. Gellermann J, Weber L, Pape L. et al. Mycofenolate Mofetil versus Cyclosporin A in children with frequently relapsing nephrotic syndrome. J Am Soc Nephrol 2013; 24(10):1689-1697
72. Lombel RM, Gipson DS, Hodson EM. Treatment of steroidsensitive nephrotic syndrome: new guidelines from KDIGO. Pediatr Nephrol 2013 Mar;28(3):415-426
Рецензия
Для цитирования:
Ныркова П.А., Савенкова Н.Д. Исследования эффективности цитостатической терапии часто рецидивирующего, гормонозависимого и со стероидной токсичностью нефротического синдрома у детей. Нефрология. 2015;19(1):30-40.
For citation:
Nyrkova P.A., Savenkova N.D. Studies of cytostatic therapy efficiency for frequently relapsing steroid dependent nephrotic syndrome with steroid toxicity in children. Nephrology (Saint-Petersburg). 2015;19(1):30-40. (In Russ.)
Просмотров:
599
Послать статью по эл. почте 