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HEMATOPOIETIC STEM CELL TRANSPLANTATION AND NEPHROPATHY

https://doi.org/10.24884/1561-6274-2018-22-1-52-57

Abstract

Hematopoietic cell transplantation (HCT) is becoming an  increasing common treatment modality for a variety  of diseases. Kidneys  are recognized as a target organ of acute and  chronic graft-versus host disease (GvHD).Glomerulopathy significantly limits patient life-time. Acute kidney injury occurs on average in 100 days after  HCT in 15 – 73% of patients due  to treatmentrelated toxity and radiation. Chronic GvHD is associated with chronic kidney disease. The majority of CKD after  transplantation is idiopathic syndrome, thrombotic microangiopathy and  nephrоtic syndrome.

About the Authors

N. B. Kuprienko
Pavlov First Saint Petersburg State Medical University; Almazov National Medical Research Centre
Russian Federation

Smirnova Natalia N - MD, PhD, DmedSci, Prof., department of pediatrics.

197022, St-Petersburg, L.Tolstoy str., 6-8, (921) 420-49-31



N. N. Smirnova
Pavlov First Saint Petersburg State Medical University; Almazov National Medical Research Centre
Russian Federation

Kuprienko Natalja B. - Senior lecturer, department of pediatrics.

197022, St-Petersburg, L.Tolstoy str., 6-8,  8-951-643-80-86



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Review

For citations:


Kuprienko N.B., Smirnova N.N. HEMATOPOIETIC STEM CELL TRANSPLANTATION AND NEPHROPATHY. Nephrology (Saint-Petersburg). 2018;22(1):52-57. (In Russ.) https://doi.org/10.24884/1561-6274-2018-22-1-52-57

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ISSN 1561-6274 (Print)
ISSN 2541-9439 (Online)