HEMATOPOIETIC STEM CELL TRANSPLANTATION AND NEPHROPATHY
https://doi.org/10.24884/1561-6274-2018-22-1-52-57
Abstract
Hematopoietic cell transplantation (HCT) is becoming an increasing common treatment modality for a variety of diseases. Kidneys are recognized as a target organ of acute and chronic graft-versus host disease (GvHD).Glomerulopathy significantly limits patient life-time. Acute kidney injury occurs on average in 100 days after HCT in 15 – 73% of patients due to treatmentrelated toxity and radiation. Chronic GvHD is associated with chronic kidney disease. The majority of CKD after transplantation is idiopathic syndrome, thrombotic microangiopathy and nephrоtic syndrome.
About the Authors
N. B. KuprienkoRussian Federation
Smirnova Natalia N - MD, PhD, DmedSci, Prof., department of pediatrics.
197022, St-Petersburg, L.Tolstoy str., 6-8, (921) 420-49-31
N. N. Smirnova
Russian Federation
Kuprienko Natalja B. - Senior lecturer, department of pediatrics.
197022, St-Petersburg, L.Tolstoy str., 6-8, 8-951-643-80-86
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Review
For citations:
Kuprienko N.B., Smirnova N.N. HEMATOPOIETIC STEM CELL TRANSPLANTATION AND NEPHROPATHY. Nephrology (Saint-Petersburg). 2018;22(1):52-57. (In Russ.) https://doi.org/10.24884/1561-6274-2018-22-1-52-57